Huidige banen gerelateerd aan Transmembrane Protein Mimics for Communication - Amsterdam Oost - AMOLF
-
Transmembrane Protein Mimics for Communication
4 maanden geleden
Amsterdam Oost, Nederland AMOLF Voltijd**Transmembrane protein mimics for communication between synthetic cells**: **Work Activities**: More about the project Functionalizing synthetic cells with transmembrane proteins is still a technical bottleneck. You will circumvent the need to solve this technical challenge time and again by generating a modular toolbox for trans-membrane protein mimics -...
-
Transmembrane Protein Mimics for Communication
4 maanden geleden
Amsterdam Oost, Nederland AMOLF Voltijd**Work Activities**: More about the project Functionalizing synthetic cells with transmembrane proteins is still a technical bottleneck. You will circumvent the need to solve this technical challenge time and again by generating a modular toolbox for trans-membrane protein mimics - an approach centered around transmembrane peptides. The central goal is to...
-
Finance Internship
3 weken geleden
Amsterdam, Nederland Jack Link's Protein Snacks Voltijd**Company Description** Make a difference in the world of branded protein snacking as Finance Intern at Jack Link’s EMEA. About Our family owned and value driven business is dedicated to crafting protein-packed snacks that are loved by consumers worldwide. Our array of brands include some of the fastest growing and innovating protein snack brands such as...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob SummaryThis is a research position in the Computational Soft Matter Lab at the Universiteit van Amsterdam. The successful candidate will work on developing and applying a computational framework for predicting nanoplastic impact on protein function.Key ResponsibilitiesAutomate descriptor discovery for chemical and conformational transitions of proteins...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob DescriptionWe are seeking a highly motivated and skilled PhD researcher to join our team at the Universiteit van Amsterdam. The successful candidate will be part of the Computational Soft Matter Lab and will work on developing and applying a forefront computational framework for predicting nanoplastic impact on protein function.Key...
-
Communications & PR Associate
3 maanden geleden
Amsterdam, Nederland Fashion For Good Voltijd**ABOUT THE JOB**: Fashion for Good is looking for a full-time PR & Communications Associate to strengthen and support the Marketing and Communications team. You will assist in day-to-day communication work streams and execute the PR and communications strategy for Fashion for Good. This includes identifying key press, journalists and industry players and...
-
Technician Qc Protein Analytics
4 maanden geleden
Amsterdam, Nederland Wacker Chemie AG VoltijdDo you want to take responsibility and make a difference with your work? With your expertise, we can achieve great goals together. We are WACKER - Reliable. Determined. Ambitious. As one of the world's most research-intensive chemical companies, we've been making countless products that are an integral part of your everyday life possible for over 100 years....
-
Technician QC Protein Analytics
3 maanden geleden
Amsterdam, Nederland Wacker VoltijdDo you want to take responsibility and make a difference with your work? With your expertise, we can achieve great goals together. We are WACKER - Reliable. Determined. Ambitious. As one of the world's most research-intensive chemical companies, we've been making countless products that are an integral part of your everyday life possible for over years....
-
Postdoc: Chaperone-guided Formation of Single
4 maanden geleden
Amsterdam Oost, Nederland AMOLF Voltijd**Postdoc: Chaperone-guided formation of single protein complexes**: **Work Activities**: Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. Our research group has been at the vanguard of studying chaperone-protein interactions using...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob DescriptionWe are seeking a highly motivated and skilled PhD candidate to join our team at the Universiteit van Amsterdam. The successful candidate will be part of a forefront research project focused on developing and applying a computational framework for predicting nanoplastic impact on protein function.Key ResponsibilitiesAutomate descriptor...
-
Marketing Assistant Emea
4 dagen geleden
Amsterdam, Nederland Jack Link's Protein Snacks Voltijd**Company Description** Our family owned and value driven business is dedicated to crafting protein-packed snacks that are loved by consumers worldwide. Our array of brands includes some of the fastest growing and innovating protein snack brands such as Jack Link's, BiFi and Peperami. Our spacious and modern Jack Link’s EMEA headquarters is located in the...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob DescriptionWe are seeking a highly motivated and skilled PhD researcher to join our team at the Universiteit van Amsterdam. The successful candidate will be part of the Computational Soft Matter Lab and will work on developing and applying a forefront computational framework for predicting nanoplastic impact on protein function.Key...
-
Phd in Biophysics: Chaperone-guided Formation of
4 maanden geleden
Amsterdam Oost, Nederland AMOLF Voltijd**PhD in Biophysics: Chaperone-guided formation of single protein complexes**: **Work Activities**: Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. Our research group has been at the vanguard of studying chaperone-protein...
-
Postdoc: Chaperone-guided Formation of Single
4 maanden geleden
Amsterdam Oost, Nederland AMOLF Voltijd**Work Activities**: Do you want to discover how multi-protein assemblies are produced without error? The aim of this project is to reveal this vital cellular process at the single-molecule level. Our research group has been at the vanguard of studying chaperone-protein interactions using optical tweezers, which allows one to follow the movements and folding...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob DescriptionWe are seeking a highly motivated and skilled PhD researcher to join our team at the Universiteit van Amsterdam. The successful candidate will be part of the Computational Soft Matter Lab and will work on developing and applying a forefront computational framework for predicting nanoplastic impact on protein function.Key...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdJob DescriptionWe are seeking a highly motivated and skilled PhD candidate to join our team at the Universiteit van Amsterdam. The successful candidate will be part of a forefront research project focused on developing and applying a computational framework for predicting nanoplastic impact on protein function.Key ResponsibilitiesAutomate descriptor...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdRole Overview This research initiative aims to create and implement a cutting-edge computational framework to forecast the effects of nanoplastics on protein functionality. Your responsibilities will include: • Automating the discovery of descriptors related to chemical and conformational transitions of proteins in the presence of nanoplastics; •...
-
Amsterdam, Nederland University of Amsterdam VoltijdDo you enjoy working on interdisciplinary research at the crossroads of physics, chemistry, biology and computational science? Are you interested in using simulations and artificial intelligence to understand key molecular processes for human and planetary health? The Van ‘t Hoff Institute for Molecular Sciences (HIMS) and the Informatics Institute (IvI)...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdRole Overview This research initiative aims to establish and utilize an advanced computational framework to forecast the effects of nanoplastics on protein functionality. Your responsibilities will include: • Automating the identification of descriptors for chemical and conformational changes in proteins interacting with nanoplastics; • Executing...
-
Amsterdam, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? This project focuses on developing and applying a forefront computational framework for predicting nanoplastic impact on protein function. You will: • Automate descriptor discovery for chemical and conformational transitions of proteins interacting with nanoplastics; • Perform machine learning-augmented free-energy...
Transmembrane Protein Mimics for Communication
3 maanden geleden
Transmembrane protein mimics for communication between synthetic cells:
Work Activities:
More about the project
Functionalizing synthetic cells with transmembrane proteins is still a technical bottleneck.
You will circumvent the need to solve this technical challenge time and again by generating a modular toolbox for trans-membrane protein mimics - an approach centered around transmembrane peptides.
The central goal is to have a protocol for firstly integrating a transmembrane peptide in lipid vesicles (phase-transfer, microfluidics), and then functionalizing it in a second step with an extracellular component for signal sensing and an intracellular component for signal propagation via bio-orthogonal chemistries.
In short:
you will work on bio-inspired communication across synthetic membranes without the need for laborious transmembrane protein purification/insertion or transport across the membranes.
The modular "LEGO" approach means that it would open a general route for generating bespoke artificial receptors for bottom-up synthetic biology in the future.
In order to answer these questions, you will integrate methods from synthetic biology and biochemistry to create functionalized lipid vesicles, and use (single-molecule) fluorescence microscopy to study their properties.
More about the SigSynCell MSCA Doctoral Training NetworkQualifications:
You are an experimental (bio)chemist or molecular biologist with a strong interest in synthetic biology and/or biophysical questions. Experience with either protein purification, handling lipids or fluorescence microscopy would be an advantage. You should like the idea of working in a diverse, collaborative, ambitious and international environment. Excellent verbal and written English skills are essential. You will need to hold an MSc-degree, to ensure eligibility for a Dutch PhD examination.
IMPORTANT:
for this position, you must also meet the EU's "Mobility conditions":
- MSCA networks require that applicants must not have studied/worked in the host country for more than 12 months in the 3 years immediately prior to the position's start date.
- This project's Host Institution is AMOLF, but a part of your doctoral studies will be spent in the laboratory of a consortium member (likely 6 months, the maximum being 12 months).
Work environment:
Working conditions:
- IMPORTANT: in line with Dutch regulations, this PhD project has a duration of 48 months, i.
More information?:
For further information about the position, please contact dr
Kristina Ganzinger:
dr. Kristina Ganzinger
Group leader Physics of Cellular Interactions
Phone:
Application:
Please annex your:
- Resume;
- Motivation on why you want to join the group (max. 1 page).
Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.
Diversity code:
AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).
