Electrophysiologist / Scientist

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Are you the dedicated scientist with a Biology or Neuroscience who is detail oriented and likes to be part of groundbreaking research?

To join our team at Charles River Laboratories at our site in Groningen we are looking for an

ex vivo Electrophysiologist
 

Our site:
Our Groningen CNS specialized site is a dedicated group where we perform discovery level research. We focus on non-GLP DMPK (drug metabolism and pharmacokinetics) and pharmacology studies to better understand neuroscience disease pathophysiology. including but not limited to, microdialysis, electrophysiology, pharmacokinetic screening and bioanalysis. 

Your roll:
In this position you will be responsible for designing, planning, performing and reporting of sponsor requested electrophysiology studies. Studies are based on ex vivo single cell or slice recordings. Manual Patch-Clamp and Multi Electrode Array are the techniques you will be using to conduct your studies with. The hands on work is often more individual, but for the entire study you will be collaborating together with scientific staff and animal technicians. You will bring in hands-on expertise to transfer and establish methods and to obtain high quality data. 

Responsibilities:
Your responsibilities will include data collection and analysis as well as data interpretation and communication of results internally and externally. You ensure that study aims are reached and work follows relevant protocols, guidelines and legislation. CRL is committed to support the 3Rs and you have an equally strong sense of applying this to the research. 

Qualifications: 

• Advanced academic degree in the life sciences; 
• Understanding of neuroscience on the cellular and systems level; 
• Experience with patch clamp measurements in cultured cells and/or acute slices and/or experience with multi electrode array measurements in acute slices;
• Programming skills and understanding of principles of electronics; 
• Fluency in English, oral and written; 
• Ability to coordinate and prioritize; 
• Excellent communication, loves a scientific challenge and positive attitude.

Nice to have:

• Experience with in vivo extracellular electrophysiology will be an asset 
• Knowledge of neuropharmacology and / or drug development processes will be an asset
• Article 9 (Laboratory Animal Science)

Our offer:
Working at our organization means working in a dynamic international organization. In addition, we offer excellent primary and secondary working conditions including:  

• 25 vacation days
• Possibility to purchase 10 additional vacation days per year;  
• Annual one-time 8% vacation pay of your gross annual salary;  
• Annual one-time payment based on company results;  
• Travel allowance at € 0.21 cents per kilometer with a maximum of € 225 net per month, 
• Collective Aegon Capitall pension with a personal contribution of 2.9%;  
• Collective health insurance with CZ or VGZ. 10 to 12% discount on any supplementary insurance. 

About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.