Huidige banen gerelateerd aan Phd Position in Molecular Control of - Utrecht - Universiteit Utrecht
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Phd Position in Molecular Control of
2 dagen geleden
Utrecht, Nederland Universiteit Utrecht VoltijdThe immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate how plants control their growth during and after an immune response. This research...
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Technician Molecular Biology
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Utrecht, Utrecht, Nederland CheckMark VoltijdWhat will your job be As a Technician Molecular Biology - Robotics you will perform molecular biological procedures using state-of-the-art liquid handling robotics systems You perform molecular biological procedures such as RNA isolation, cDNA synthesis, PCR and cloning with the help of state-of-the-art liquid handling robotics systems You will...
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Phd Position On Proteomics: The Biology of Protein Lipidation
4 dagen geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdJoin our multidisciplinary team to explore the dynamic world of protein lipidation in (neuro)inflammation. We are offering two PhD positions focused on uncovering the regulation and biological roles of this crucial posttranslational modification. Using cutting-edge proteomics and chemical biology tools, you will contribute to advancing our understanding of...
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PhD Position on Proteomics: The Biology of Protein Lipidation
5 dagen geleden
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdJoin our multidisciplinary team to explore the biology of protein lipidation in (neuro) inflammatory disorders.Join our multidisciplinary team to explore the dynamic world of protein lipidation in (neuro)inflammation. We are offering two PhD positions focused on uncovering the regulation and biological roles of this crucial posttranslational modification....
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PhD Position in Developmental Biology
3 dagen geleden
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PhD Position in Solid-state NMR and Drug Discovery
2 weken geleden
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdAre you an ambitious researcher? We have 3 positions available in the fields of structural biology (NMR) and antibiotics (Gram-negatives and Mycobacteria).Are you a highly motivated and ambitious researcher? Join us as a PhD candidate. We have three positions available in the fields of structural biology (NMR) and antibiotics (Gram-negatives and...
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Phd Position: Exploring Microbial Potential for
2 weken geleden
Utrecht, Nederland Universiteit Utrecht VoltijdPFAS (per - and polyfluoroalkyl substances) are so-called ‘’forever chemicals’’ that are found everywhere: in our soils, water, food and bodies. PFAS contamination of soils is an increasingly important global issue, and we still lack sustainable methods for PFAS remediate. The PFAS Remediation Living Lab is a contaminated location at the Utrecht...
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PhD Position on Abiotic Stress-Mediated Flowering
2 weken geleden
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Phd Student Explainable Ai
1 week geleden
Utrecht Oost, Nederland Prinses Máxima Centrum VoltijdThe Kemmeren group, in collaboration with the de Ridder group, is looking for an enthusiastic, highly motivated PhD student who excels in a stimulating, multi-disciplinary research environment and can drive forward our ambition to develop explainable AI models in pediatric cancer. **Tasks and responsibilities** **Profile** **Our job offer** A full time...
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Technician (Molecular Biology)
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Phd Position in Philosophy of Science
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Utrecht, Nederland Universiteit Utrecht VoltijdScience communication often involves hyped, overly broad claims about research findings. What are the causes, social epistemological risks, and who’s responsible? In this PhD project, you will be researching these questions. **Your job**: We are offering a fully funded four-year PhD position to a researcher interested in philosophically and experimentally...
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PhD Position in Microbial Drivers of Peat Oxidation
2 weken geleden
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdAre you passionate about environmental science and eager to contribute to climate solutions? Make your research count and join our research team.Are you passionate about environmental science and eager to contribute to climate solutions? Utrecht University is looking for a PhD candidate to investigate the role of microbial communities in peat oxidation. Join...
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Phd and Postdoc Positions On Global Delta Modelling
3 dagen geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdRiver deltas have been growing for thousands of years, but their future is uncertain. Internal geomorphological feedbacks may push deltas past a tipping point, leading to rapid land loss. This project aims to quantify the life expectancies of global deltas. We offer two positions — a PhD on Holocene delta modelling and a PhD or postdoc on human impact —...
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PhD Position in Neurotoxicology
2 weken geleden
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdDo you want to unravel the role of environmental chemicals in neurodegeneration? Join our team Will you join the Toxicology division of Institute for Risk Assessment Sciences (IRAS)? In this PhD project, you will be working on different activities and projects, all focused on improving in vitro toxicity testing.Your jobWe are seeking an enthusiastic and...
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Phd Student
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Utrecht, Nederland Koninklijke Nederlandse Akademie van Wetenschappen Voltijd**Location**:Utrecht **Max hours per week**:38.00 **Max salary**:3.670 **Duration of agreement**:15 months (extend after evaluation) **A fully-funded PhD position is immediately available in the new research group led by Miguel Leung, which opens at the Hubrecht Institute in October 2024.** **What you will be doing** The Leung group uses cellular...
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Phd Position in The Field of Climate Tipping
2 dagen geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdJoin us at the Copernicus Institute for a PhD position exploring the critical interactions between two climate tipping elements: the Atlantic Meridional Overturning Circulation (AMOC) and the Amazon rainforest. As part of the EMBRACER programme, you’ll use advanced models and data analysis to uncover how these systems influence each other and the global...
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Phd Position improvising Security: Subsistence in
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Utrecht Binnenstad, Nederland Universiteit Utrecht Voltijd**Your job**: We are hiring a PhD researcher to participate in the NWO/Vidi project **"I**mprovising Security: Subsistence in Contemporary Urban Europe**"** and to write a dissertation based on urban ethnographic research in Rotterdam, the Netherlands. Urban dwellers in Western Europe are facing new insecurities related to work, care, and access to basic...
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Phd Positions: Mechano-catalytic Depolymerisation
3 dagen geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdAre you looking to do a PhD project and are you interested in catalysis, spectroscopy, mechano-chemistry, or polymer science to develop a sustainable pathway for plastic waste recycling through mechano-catalytic conversion? Join us in shaping a greener future! **Your job**: The core objective of this project is to pioneer the conversion of polyolefins into...
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PhD Position in Marine Palynology
1 week geleden
Utrecht, Utrecht, Nederland Utrecht University VoltijdThe is looking for a highly motivated PhD candidate with an MSc Palynology, Micropaleontology, Organic Geochemistry and/or Oceanography. You will work on the project "Ice-ocean interactions in West Antarctica during rapid transitions in past warm climates". In this four-year study, you will reconstruct in detail the oceanographic changes close to the...
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PhD Position on Climate Dynamics
4 dagen geleden
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdJoin the team and research the interactions between the Atlantic Ocean circulation and the Amazon RainforestJoin the Institute for Marine and Atmospheric Research Utrecht (IMAU) and research the interactions between the Atlantic ocean circulation and the Amazon Rainforest.Your jobThe Atlantic Meridional Overturning Circulation (AMOC) and the Amazon...
Phd Position in Molecular Control of
4 weken geleden
The immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate the poorly understood process of how plants control their growth during and after an immune response. You will capitalise on the available extensive lettuce gene expression and high-throughput phenotyping datasets.
**Your job**:
Current projections show that the incidence of diseases on crops will increase in the coming decades, and thus, conceptually new strategies, beyond strengthening the immune system, are needed to ensure the resilience of future crops. It turns out that plants slow down their growth during and after an immune response regardless of the disease intensity. However, how these growth processes are regulated in plants is unclear. In this curiosity-driven PhD project, you will uncover the genetic and molecular basis of plant growth during and after an immune response. With this knowledge, one could develop approaches that reduce this tradeoff in crop growth. You will primarily work with lettuce (_Lactuca sativa_), but conservation of the deduced concepts can be investigated in other plant species, such as _Arabidopsis thaliana_.
Your project will capitalise on two types of datasets generated during the LettuceKnow programme. The first dataset includes large and dense time-course RNAseq experiments, where we activated the lettuce immune system and tracked the transcriptome changes over several hours. The second dataset includes high-throughput digital phenotyping data for the growth of ~180 lettuce varieties in the presence of defense hormones and after their removal (the recovery phase). This dataset was obtained with the Netherlands Plant Ecophenotyping Center (NPEC).
In the first phase of the project, you will utilise bioinformatics, genome-wide association mapping (GWAS), and machine learning techniques to identify new players of plant growth during and after an immune response. You will validate the genetic leads, such as transcription factors (TFs), identified in our earlier research. In the second phase of the project, you will work on the functional validation and characterization of the identified regulators of immunity-conditioned growth (e.g., TFs) using CRISPR-Cas gene editing and alteration of gene expression in lettuce and Arabidopsis. For selected targets, you will use quantitative proteomics and chromatin-protein interaction assays to gain insights into the activity of protein complexes driving growth during and after an immune response. Similarly, high-throughput digital phenotyping of mutants and overexpression lines in NPEC can be used to investigate their impact on inferred regulatory pathways.
We currently have another PhD position on growth-immunity tradeoffs available in Dmitry Lapin’s team. For more information about this position, check out our website.
**Your qualities**:
We are looking for a collaborative, enthusiastic, and curiosity-driven colleague who:
- has a completed MSc degree or is about to get an MSc degree in molecular and/or computational biology;
- has an affinity to experimental (plant) biology research;
- has demonstrated skills in either or both computational and molecular biology research;
- wants to learn, deploy, or even develop new methods of computational and molecular biology research.
**Our offer**:
- We offer:
- a position for 4 years;
- a gross monthly salary between €2,770 and €3,539 in the case of full-time employment (salary scale P under the Collective Labour Agreement for Dutch Universities (CAO NU);
- 8% holiday pay and 8.3% year-end bonus;
- a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.
In addition to the terms of employment laid down in the CAO NU, Utrecht University has a number of schemes and facilities of its own for employees. This includes schemes facilitating professional development, leave schemes and schemes for sports and cultural activities, as well as discounts on software and other IT products. We also offer access to additional employee benefits through our Terms of Employment Options Model. In this way, we encourage our employees to continue to invest in their growth. For more information, please visit Working at Utrecht University.
**About us**:
A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. Sharing science, shaping tomorrow.
At the Faculty of Science there are 6 departments to make a fundamental connection with: Biology, Chemistry, Information and Computing Sciences, Mathematics,
