Intern - Immunology/biochemistry - Discovery &

We are looking for a motivated fourth-year HBO or WO student Do you want to know what it's like to be part of one of the largest multinational companies in the pharmaceutical industry? We offer an internship opportunity within our Discovery & Technology department where you will have the freedom and space for your own initiative.

**Intern - Immunology/Biochemistry - Discovery & Technology**

**Welcome to our team**

The Discovery & Technology (D&T) department is an essential hub in our organization. This department is focused on the early stage pipeline by evaluating novel technologies to develop novel products. The team consists of roughly 40 employees, all of whom have extensive knowledge and experience in molecular biology, virology, microbiology, immunology, formulation and assay development. The team works closely with other departments within the company to achieve the stated goals.

**Your internship assignment**:
Currently, a cross-departmental project (D&T and Biotechnology Solutions (BTS) departments) is focusing on the development of an established recombinant antibody workflow that ultimately creates an alternative procedure for the generation of monoclonal antibodies for replacing mice immunization activities which are currently the standard procedure. The success rate for identification of B cell clones that secrete antigen-specific immunoglobulins with high affinity depends however largely on optimized procedures for the screening and isolation of antigen-specific B-lymphocyte subsets from blood of the respective host species.

The focus of this internship project will be on developing procedures for isolation of antigen-specific bovine B cell clones derived from whole blood of immunized cattle by means of multi-color flow cytometry-based phenotyping and sorting procedures. Quality of B-cell clone produced antibodies will be evaluated using various analytical methodologies and compared against existing hybridoma-derived monoclonal antibodies.

**Your responsibilities**
- Primary cell isolation and flow cytometry technologies
- ELISA and Octet analyses
- Cell culture and recombinant protein expression/purification
- Providing a fresh perspective within the department: your opinion matters

The described tasks form the basic package and will often be performed independently after a proper training and learning period. These tasks may be supplemented with other projects and/or tasks on your own initiative or at the request of the organization.

**What is required**
- A fourth-year Bachelor student (Applied sciences) or Master student immunology/biochemistry
- You are enthusiastic about working on vaccine development, have a professional attitude, are enthusiastic, eager to learn new techniques and challenged to do an internship in a dynamic multidisciplinary environment.
- You are searching for an internship where you may have the freedom to take initiative
- You are fluent in Dutch or English; preferentially both
- You are available for a period of 6-9 months for 5 days a week.

**What we offer**

Interning at our company means working together with your team towards health in an international work environment. As an intern, you will have the opportunity to work closely with experts and learn from them. In addition, we offer:

- The chance to gain experience in the pharmaceutical industry
- An opportunity to showcase yourself for potential opportunities after your internship period
- A challenging and dynamic work environment with plenty of room for personal development and initiative
- Good guidance from an experienced specialist
- A gross monthly internship allowance of €500;
- based on a 40-hour workweek

**Animal Health Division**:
Our Animal Health Division is a trusted global leader in animal healthcare. We are committed to preserving and improving the health, well-being, and performance of animals and the people who care for them. As a global team of professionals, we work together to make a positive difference in animal care and the world's food chain. We also have a deep sense of responsibility towards our customers, consumers, animals, society, and our planet.

By being dedicated to The Science of Healthier Animals®, we provide veterinarians, farmers, pet owners, and governments with one of the broadest ranges of animal health products, vaccines, and solutions and services for health management. Additionally, we deliver a comprehensive range of digitally connected identification, traceability, and monitoring products. We invest in dynamic and extensive R&D capabilities and a modern, global supply chain. We are present in more than 50 countries, and our products are available in approximately 150 markets.

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**Employee Status**:
Intern/Co-op (Fixed Term)

**Relocation**:
**VISA Sponsorship**:
**Travel Requirements**:
**Flexible Work Arrangements**:
Not Applicable

**Shift**:
**Valid Driving License**:
**Hazardous Mate