Postdoc Researcher in Liver Models for Toxicity

4 weken geleden

Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

**Your function**:
We are looking for a motivated Postdoc with a strong background in advanced human cell culture systems, including organoids, and in molecular toxicology.

**Your duties**
- Development of induced pluripotent stem cell (iPSC)-derived liver models, including organoids derived of hepatocytes and non-parenchymal cells
- Characterisation of functional phase I and II metabolism
- Data analysis and integration of several toxicology assays, including Seahorse bioanalyser (mitochondria toxicity) and transcriptomics datasets
- High Content Imaging
- Publish scientific articles and present research results at conferences;
- Collaborate within the team and with other international researchers

**Your profile**:

- PhD obtained within the last 5 years within the discipline of either toxicology, pharmacology, cell -or developmental-biology or a related discipline;
- Strong expertise in 3D human cell culture and iPSC, ideally with liver models
- Background in toxicology and mechanistic assays
- Aptitude for data handling and analysis; Transcriptomics analysis is a plus
- Experience with analytical methods (LC-MS) is an advantage
- Good communication, organizational and social skills;
- High proficiency in speaking and writing in the English language;
- Team player with the ability to work independently;
- Strong motivation for scientific research

As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.

We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements.

**What do we offer?**:
A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:

- a salary of minimum € 3.226,00 (Scale 10) and maximum € 5.090,00 (Scale 10) gross per month, on a full-time basis. This is based on UFO profile Researcher 4. The exact salary depends on your education and experience.
- a position for at least 0.8 FTE. Your employment contract will initially last 1 year.

We also offer you attractive fringe benefits and regulations. Some examples:

- A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.
- 8% holiday allowance and 8.3% end-of-year bonus
- space for personal development
- a wide range of sports facilities which staff may use at a modest charge
- discount on (and occasionally exclusive access to) theater performances and courses at the Griffioen Cultural Center

**About us**:
**Division of Molecular and Computational Toxicology**
At the division of Molecular and Computational Toxicology section, dept of Chemistry and Pharmaceutical Sciences research is carried out to study the molecular mechanisms underlying the toxic effects of drugs and other chemicals. Using innovative human cellular model systems, state-of-the-art metabolomics approaches and computer simulation methods, the mechanism by which chemicals can cause adverse effects are investigated. The section is also involved in education within Bachelor's and Master's degree programs in Pharmaceutical Sciences, Chemistry, Medical Natural Sciences and Biomolecular Sciences.

**Faculty of Science**
Researchers and students at VU Amsterdam’s Faculty of Science tackle fundamental and complex scientific problems to help pave the way for a sustainable and healthy future. From forest fires to big data, from obesity to malnutrition, and from molecules to the moon: we cover the full spectrum of the natural sciences. Our teaching and research have a strong experimentally technical, computational and interdisciplinary nature.

We work on new solutions guided by value-driven, interdisciplinary methodologies. We are committed to research, valorisation and training socially engaged citizens of the world who will make valuable contributions to a sustainable, healthy future.

**Vrije Universiteit Amsterdam**
Vrije Universiteit Amsterdam stands for values-driven education and research. We are open-minded experts with the ability to think freely. - a broader mind. Maintaining an entrepreneurial perspective and concentrating on diversity, significance and humanity, we work on sustainable solutions with social impact. By joining forces, across the boundaries of disciplines, we work towards a better world for people and planet. Together we cre

  • Postdoc in Modeling of Seasonal Host-parasite Dynamics

    2 weken geleden

    Amsterdam, Nederland Universiteit van Amsterdam Voltijd

    Postdoc in Modeling of Seasonal Host-parasite Dynamics **Faculty/Services**:Faculty of Science **Educational level**:PhD **Function type**:Postdoc **Closing date**:31 January 2025 **Vacancy number**:13680 - Are you an expert in mathematical modeling of population dynamics and/or infectious diseases? Are you experienced with using compartment models...

  • Postdoc Position On Multimodal Foundation Models

    4 weken geleden

    Amsterdam, Nederland Universiteit van Amsterdam Voltijd

    Postdoc Position on Multimodal Foundation Models **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Gepromoveerd**Functie type**:Wetenschappelijk Personeel**Sluitingsdatum**:20 september 2024**Vacaturenummer**:13359 **Are you interested in performing high-impact artificial intelligence research on multimodal foundation...

  • Postdoc: Bioassays for Antimicrobial Resistance

    4 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Your function**: Antimicrobial resistance (AMR) is increasing morbidity, mortality, and health-care expenditures worldwide. The (semi-)natural aquatic environment functions as an important reservoir and dissemination route of antimicrobial resistance genes (ARGs), where bacteria carrying these ARGs can proliferate in the presence of antibiotic residues and...

  • Quantitative Researcher

    3 weken geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher - HFT (Options) Location - Amsterdam, can be remote from USA/UK Base salary - up to €500k Bonus - 100-300% We are looking for a Quantitative Researcher to join an algorithmic trading company based in Amsterdam, who have just been acquired by a large international trading company so you have best of both worlds, working for a...

  • Research Technician Ipsc Models for Vascular Ocular

    3 weken geleden

    Amsterdam-Zuidoost, Nederland Amsterdam UMC Voltijd

    **About the project**: As a research technician, you will support the researchers of the Ocular Angiogenesis Group of the Department of Ophthalmology. We focus on vascular diseases of the retina, such as diabetic retinopathy and macular degeneration. In our research, you will work with vascular organoids derived from patient-specific stem cells (iPSCs)....

  • 3 Postdoc Positions in Human-robot-bonding

    4 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Jouw functie**: **Your duties** **Postdoc-1** (0.8 fte, 4 yr) will focus on robot-assisted education for children with ‘special needs’ (e.g., ASD), and thus, contribute to developing a robot as tutor for special educational tasks. **Postdoc-2 **(0.8 fte, 4 yr) will focus on (physically) disabled (young) adults to be accompanied by a robot to reduce...

  • Quantitative Researcher

    3 weken geleden

    Amsterdam Metropolitan Area, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher - HFT (Options)Location - Amsterdam, can be remote from USA/UKBase salary - up to €500k Bonus - 100-300%We are looking for a Quantitative Researcher to join an algorithmic trading company based in Amsterdam, who have just been acquired by a large international trading company so you have best of both worlds, working for a start-up...

  • Phd and Postdoc Positions at Vusec

    2 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Your function**: VUSec performs world-leading research in the broad area of systems security. We work on attacks, defenses, reverse engineering, and formal verification of security. We cover all major areas where security is important, especially software security, hardware security, and network security. We love to work on low-level stuff, for example...

  • Postdoctoral Researcher: The Economics of Housing

    3 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Your function**: The project focuses on housing affordability in the Netherlands Denmark and UK over the last 50 years. It aims to evaluate policies regarding public housing, urban renewal and rental regulation estimating reduced form and quantitative equilibrium models. The postdoc will cooperate with PhD students as well as professors within the...

  • Assistant Researcher Digable 'media-interventions and Neurodivergent Youth'

    3 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Your function**: While recognition and respect for neurodiversity are growing, the impact of large societal shifts, such as digitalization, is felt disproportionally by a broad group of neurodivergent youth (including borderline to mild intellectual disability-MID, autism and ADHD). Media-lessons and -interventions for the general youth population have...

  • Quantitative Researcher

    1 dag geleden

    Amsterdam, Noord-Holland, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher – Elite Proprietary Trading FirmBase Salary: Up to €300,000 per annum + bonusLocation: Amsterdam, on siteWe're seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a performance-driven bonus,...

  • Researcher (Data Analysis)

    3 weken geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Location - Amsterdam, can be remote from USA/UK We are looking for a Quantitative Researcher to join an algorithmic trading company based in Amsterdam, who have just been acquired by a large international trading company so you have best of both worlds, working for a start-up but with the backing and security of a large multinational. Their models and...

  • Quantitative Researcher

    5 dagen geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher – Elite Proprietary Trading FirmBase Salary: Up to €300,000 per annum + bonusLocation: Amsterdam, on siteWe’re seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a performance-driven bonus,...

  • Quantitative Researcher

    5 dagen geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher – Elite Proprietary Trading Firm Base Salary: Up to €300,000 per annum + bonus Location: Amsterdam, on site We’re seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a...

  • Quantitative Researcher

    2 dagen geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher – Elite Proprietary Trading FirmBase Salary: Up to €300,000 per annum + bonusLocation: Amsterdam, on siteWe’re seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a performance-driven bonus,...

  • Quantitative Researcher

    1 dag geleden

    Amsterdam, Noord-Holland, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher - Elite Quantitative Trading Company Base Salary: Up to €300,000 per annum base + bonus Location: Amsterdam, on site We're seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a...

  • Postdoc Landscape Ecology for Digital Twins

    3 weken geleden

    Amsterdam, Nederland Universiteit van Amsterdam Voltijd

    Postdoc Landscape Ecology for Digital Twins **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Gepromoveerd**Functie type**:Researcher**Sluitingsdatum**:15 november 2024**Vacaturenummer**:13520 - Are you an expert in landscape ecology with interest in studying spatial patterns and relationships between species and their...

  • Researcher (Data Analysis)

    5 dagen geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher – Elite Proprietary Trading Firm We’re seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a performance-driven bonus, highlighting the role’s importance in the firm’s technology-first,...

  • Postdoc

    4 weken geleden

    Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

    **Your function**: As a postdoctoral researcher, you will be responsible for the design, fabrication, and characterization of photonic microcircuits used to stimulate biological neurons cultured on top of them. You will develop and optimize these integrated photonic devices, ensuring their precision and functionality for neural stimulation. Additionally, you...

  • Quantitative Researcher

    3 weken geleden

    Amsterdam, Nederland Understanding Recruitment Voltijd

    Quantitative Researcher - Elite Quantitative Trading CompanyBase Salary: Up to €300,000 per annum base + bonusLocation: Amsterdam, on siteWe're seeking a skilled Quantitative Researcher to join an advanced research team within a leading trading firm in Amsterdam. This role offers an exceptional base salary of up to €300,000, plus a performance-driven...