PhD Position Additively manufactured biodegradable bone substitutes with tunable degradation

PhD Position Additively manufactured biodegradable bone substitutes with tunable degradation

Design the next generation of biodegradable, additively manufactured bone substitutes. Combine materials, mechanics, and machine learning to shape patient-specific regenerative implants

Job description

Faculty of Mechanical Engineering, TU Delft — Departments of Precision and Microsystems Engineering (PME) & Biomechanical Engineering (BME)

Are you excited by the idea of engineering next-generation regenerative implants? Do you want to combine additive manufacturing, materials science, biomechanics, and physics- and machine learning-based modeling to create transformative medical solutions? Join us in this ambitious collaboration between the PME and BME departments, and help shape the future of patient-specific bone replacement.

In this PhD project, you will develop biodegradable porous bone substitutes produced through additive manufacturing of metal-ceramic composites. These architected implants will be tailored for mechanical performance and controlled degradation, enabling safe and effective regeneration in load-bearing environments.

Your core challenge is to understand and predict how geometry, material composition, and manufacturing parameters drive quasi-static performance, biodegradation kinetics, and manufacturability. You will employ a combined physics-based and machine-learning modelling approach, supported by in-vitro mechanical and degradation experiments for validation.

The developed porous structures will integrate seamlessly with macro-geometries and topologically optimized architectures from sibling PhD projects, delivering a fully engineered, patient-specific bone-replacement solution.

This PhD position is part of a Marie Skłodowska-Curie Doctoral Network (Horizon Europe). As an MSCA Doctoral Candidate, you will join a vibrant international cohort, participate in network-wide schools and workshops, and pursue mandatory research secondments abroad. The MSCA framework offers exceptional training, mobility, and career-development opportunities

Job requirements

Your Key Responsibilities:

• Investigate the role of design parameters, architecture, material composition, and AM process settings on mechanical performance and degradation behavior.
• Develop physics-based and data-driven models to link geometry, materials, and biodegradation kinetics.
• Conduct in-vitro mechanical tests and biodegradation experiments to validate models.
• Collaborate closely with researchers at PME and BME, as well as with the wider MSCA network.
• Interface your designs with macro-scale implant geometries and topology-optimized structures from sibling projects.

Your Profile

We are looking for a highly motivated candidate with:

• Master's degree in Mechanical Engineering, Materials Science, Biomedical Engineering, Applied Physics, or a related field.
• Knowledge of additive manufacturing, biomaterials, or mechanical testing.
• Strong background in lab works including material characterization, chemical process, and in vitro testing.
• Experience with programming (e.g., Python, Julia) is a plus.
• Interest in biomechanics, biodegradable materials, and design for AM.
• Good communication skills and the ability to work in a multidisciplinary team.
• Willingness to relocate and undertake international secondments.
• Compliance with MSCA mobility rule: you must not have lived or carried out your main activity (work, studies) in the Netherlands for more than 12 months in the past 36 months.

What we offer:

• A fully funded PhD position within a prestigious MSCA Doctoral Network.
• Close supervision and mentorship from both PME and BME departments at TU Delft.
• Access to state-of-the-art additive manufacturing and experimental characterization facilities.
• Training through network-wide workshops, summer schools, and transferable-skills programmes.
• Research secondments with international academic and industrial partners.
• Collaboration with a cohort of Doctoral Candidates working toward an integrated, patient-specific implant design pipeline.

TU Delft (Delft University of Technology)

Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact

Faculty Mechanical Engineering

From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the ME faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

ME is a dynamic and innovative faculty with high-tech lab facilities and international reach. It's a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in ME's outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.

Conditions of employment

Doctoral candidates will be offered a 4-year period of employment in principle, but in the form of 2 employment contracts. An initial 1,5 year contract with an official go/no go progress assessment within 15 months. Followed by an additional contract for the remaining 2,5 years assuming everything goes well and performance requirements are met.

Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities, increasing from €3059 - €3881 gross per month, from the first year to the fourth year based on a fulltime contract (38 hours), plus 8% holiday allowance and an end-of-year bonus of 8.3%.

As a PhD candidate you will be enrolled in the TU Delft Graduate School. The TU Delft Graduate School provides an inspiring research environment with an excellent team of supervisors, academic staff and a mentor. The Doctoral Education Programme is aimed at developing your transferable, discipline-related and research skills.

The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.

Will you need to relocate to the Netherlands for this job? TU Delft is committed to make your move as smooth as possible The HR unit, Coming to Delft Service, offers information on their website to help you prepare your relocation. In addition, Coming to Delft Service organises events to help you settle in the Netherlands, and expand your (social) network in Delft. A Dual Career Programme is available, to support your accompanying partner with their job search in the Netherlands.

Additional information

For more information about this vacancy, please contact Dr. Mohammad J Mirzaali ) and Dr. Alejandro M. Aragón ).

Application procedure

Are you interested in this vacancy? Please apply no later than 29 January 2026 upload the following documents:

• CV
• Cover letter
• Transcripts
• 2 recommendation letters

Doing a PhD at TU Delft requires English proficiency at a certain level to ensure that the candidate is able to communicate and interact well, participate in English-taught Doctoral Education courses, and write scientific articles and a final thesis. For more details please check the Graduate Schools Admission Requirements.

Please note:

• You can apply online. We will not process applications sent by email and/or post.
• As part of knowledge security, TU Delft conducts a risk assessment during the recruitment of personnel. We do this, among other things, to prevent the unwanted transfer of sensitive knowledge and technology. The assessment is based on information provided by the candidates themselves, such as their motivation letter and CV, and takes place at the final stages of the selection process. When the outcome of the assessment is negative, the candidate will be informed. The processing of personal data in the context of the risk assessment is carried out on the legal basis of the GDPR: performing a public task in the public interest. You can find more information about this assessment on our website about knowledge security.
• Please do not contact us for unsolicited services.

Faculty/Department: Faculty of Mechanical Engineering

Salary range: €3059 - €3881

Hours per week: 36-40

FTE: 0,9-1,0

Submission is possible until: 29 Jan 2026

ID job: 2925

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