2 PhD positions NanoNU-Marker: Nano-Chemical Biomarkers for Ageing and Neurodegeneration

5 dagen geleden


Wageningen, Nederland Wageningen University & Research Voltijd

Your job

We are looking for two PhD students to join our recently awarded project to develop Nano-Chemical Biomarkers of Molecular Mechanisms and Nutritional Factors in Cognitive Ageing and Neurodegeneration.
Are you a highly driven, motivated and curious person loving interdisciplinary Science? Do you have an MSc degree in Physics, Chemistry or Molecular Life Sciences with focus on Biosciences? That makes a match


You will work closely together with the other PhD and develop, combine and apply innovative emerging microfluidics, nano-chemical, and digital technologies. Purpose is to unravel the molecular links between protein aggregation, nutrition/lifestyle, and the onset and progression of cognitive ageing and neurodegenerative disease in older adults. These methods will be applied to study human biofluids as a nano-chemical fingerprint of patients nutritional and life-style behavior, to identify nano-chemical biomarkers of Healthy Cognitive Ageing (PhD position 1) and Subjective Cognitive Decline (PhD position 2)

Your duties and responsibilities will include:

preparation and surface deposition of human biofluids via microfluidics; use key surface analytical methods of analysis as bulk infrared spectroscopy, optical photothermal spectroscopy, and infrared nanospectroscopy (AFM-IR); apply chemometrics and machine learning methods (AI) to analyze the data and identify nano-chemical biomarkers related to molecular and nutritional factors.

Your qualities

Are you a highly motivated and extremely curious researcher in the making? Is the why? and the how a part of your daily reasoning, both inside and outside of Science? Then you might be the perfect candidate for this position.

In summary, you have:

a MSc degree (or equivalent) in Physics, Chemistry or Molecular Life Sciences; a strong background and solid hands-on experience in experimental analytical methods, data processing, and statistical analysis; a strong interest (or preferentially: experience) in spectroscopy, microscopy, scanning probe technologies; a deep interest in applying physical methods to complex bio-samples, such as human biofluids; what it takes to work in a highly multidisciplinary, dynamic and collaborative environment and you are open to communicate to a language that is comprehensible to broad public and scientific audience. For this position your command of the English language is expected to be at C1 . Sometimes it is necessary to submit an internationally recognized Certificate of Proficiency in the English Language. More information can be found .

You will work here:
The research will be undertaken in the group of Dr. (), located within the chair groups of and . You will be working closely together with Prof.dr. Lisette de Groot (PhD-1) and dr. Yannick Vermeiren (PhD-2) from the chair group of (division Human Nutrition and Health).

The two PhD position openings are also placed in the frame of the collaboration between Dr. Ruggeri and Wageningen University with Photothermal Spectroscopy Corporation (USA) and Bruker Nano Surface (USA); who are co-founders of the project and will provide fundamental engineering support. While the project is fundamental in nature, the PhDs will have the opportunity to work at the interface between Research and Technology Development targeting biomarkers of cognitive ageing.

We offer you

Wageningen University & Research offers excellent . A few highlights from our Collective Labour Agreement include:

partially paid parental leave; working hours that can be discussed and arranged so that they allow for the best possible work-life balance; the option to accrue additional compensation / holiday hours by working more, up to 40 hours per week; there is a strong focus on vitality and you can make use of the sports facilities available on campus for a small fee; a fixed December bonus of 8.3%; excellent pension scheme. In addition to these first-rate employee benefits, you will receive a fully funded PhD position and you will be offered a course program tailored to your needs and the research team.

The gross salary for the first year is 2.770 - per month rising to 3.539,- in the fourth year in according to the (scale P). This is based on a full-time working week of 38 hours. We offer a temporary contract for 18 months which will be extended for the duration of the project if you perform well.

There are plenty of options for personal initiative in a learning environment, and we provide excellent training opportunities. We are offering a unique position in an international environment with a pleasant and open working atmosphere.

You are going to work at the greenest and most innovative campus in Holland, and at a university that has been chosen as the in the Netherlands for the 19th consecutive time.

Coming from abroad
Wageningen University & Research is the university and research centre for life sciences. The themes we deal with are relevant to everyone around the world and Wageningen, therefore, has a large international community and a lot to offer to international employees.

Because we expect you to work and live in the Netherlands our team of advisors on Dutch immigration procedures will help you with the visa application procedures for yourself.

Feeling welcome also has everything to do with being well informed. We can assist you with any additional advice and about for example helping your partner to find a job, housing, or schooling.

Finally, certain categories of international staff may be eligible for a tax exemption on a part of their salary during the first five years in the Netherlands.


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