Associate Director, Pathology

6 maanden geleden

Utrecht, Nederland Genmab Voltijd

The Role


As a Pathologist at Genmab, you will be part of an international Pathology team embedded within Precision Medicine of our Translational & Quantitative Sciences team based in Princeton, New Jersey. In this role you will work with scientists in a state-of-the-art histology and immunohistochemistry laboratory to support a variety of discovery, pre-clinical and clinical programs.

Responsibilities

The anatomic pathologist in this role will impact Genmab’s pipeline from early research to clinical trial stages, providing expertise in histopathological evaluation, tissue-based assay development (IHC, ISH, IF), biomarker strategy and toxicologic pathology for a variety of antibody therapeutics.  Scientific curiosity, strategic thinking, and the capacity to work well in cross-functional teams are important traits of the successful candidate.

You will contribute your pathology expertise by both traditional slide evaluation, and by guiding the development and interpretation of advanced tissue-based assays, such as multiplex immunofluorescence panels, digital image analysis, and machine learning image projects.

Your responsibilities include but are not limited to the following:

  • Help laboratory personnel in our US and European locations to design and develop immunohistochemistry assays for single-plex chromogenic and fluorescence, in situ hybridization (ISH) assays, multiplex IF and ISH-IF combinations (10% lab work IHC/IF assay development).

  • Support our digital pathology team and work closely with Data Sciences to develop and verify digital image analysis algorithms and results from image analysis projects.

  • Evaluate, qualitatively and quantitatively (H-Scores, % staining, etc) a variety of immunohistochemical stains for target screening and biomarker assessment.

  • Serve as in-house expert representing Genmab in interactions with CROs developing IHC and ISH assays to support our pre-clinical and clinical biomarker programs.

  • Perform, as needed, primary reads and/or peer review of pre-clinical toxicology studies, including tissue cross reactivity studies, investigative and GLP studies.

  • Provide internal expertise to understand the mechanisms of toxicity observed non-clinically or clinically in order to help design mitigation strategies and minimize risk to patients.

  • Contribute with evaluation, and implementation of new technologies and techniques for tissue-based assays and digital image analysis applications.

Requirements

  • Doctor in Veterinary Medicine or equivalent degree, with a minimum of 2-5 years of relevant experience supporting discovery and development organizations.

  • Diplomate, American College of Veterinary Pathologists (or equivalent) in anatomic pathology.

  • Graduate degree (Master’s or PhD) desired.

  • Solid experience with design and interpretation of immunohistochemistry assays and digital pathology applications.

  • Strategic thinking, innovative and collaborative mindset and a willingness to work in multidisciplinary teams.

  • Basic knowledge of statistics and data visualization software (SAS, GraphPad, Spotfire).

  • Experience managing pathology laboratories desired, but not required.

  • Background in immunology and immuno-oncology, knowledge of biomarker development and companion diagnostic development is desired but not required.

For US based candidates, the proposed salary band for this position is as follows:

$,.00---$,.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as bonuses.

About You

  • You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
  • You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
  • You are a generous collaborator who can work in teams with diverse backgrounds
  • You are determined to do and be your best and take pride in enabling the best work of others on the team
  • You are not afraid to grapple with the unknown and be innovative
  • You have experience working in a fast-growing, dynamic company (or a strong desire to)
  • You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

  • Scientific Director, Anatomic Pathology

    1 maand geleden

    Utrecht, Utrecht, Nederland Genmab Voltijd

    Role OverviewThe Anatomic Pathologist at Genmab will be a key member of our international Pathology team embedded within Precision Medicine of our Translational & Quantitative Sciences team based in Princeton, New Jersey. As a Pathologist, you will work closely with scientists in a state-of-the-art histology and immunohistochemistry laboratory to support...

  • Associate Director Holdings Controller

    6 maanden geleden

    Utrecht, Nederland Bristol-Myers Squibb Voltijd

    **Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms...

  • Associate Director, Qp Operations

    6 maanden geleden

    Utrecht, Nederland Bristol-Myers Squibb Voltijd

    **Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms...

  • (Associate) Director, Biostatistician

    6 maanden geleden

    Utrecht, Nederland Genmab Voltijd

    At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...

  • Associate Buyer

    6 maanden geleden

    Utrecht, Nederland Foot Locker Voltijd

    Overview: The Associate Buyer is an entry position into the Buyer role. The position is responsible for a category or department(s) under the coaching and supervision of the Buying Director. They will be required to meet and where possible exceed the sales, gross margin and turn targets for their relevant category or department(s). The Associate Buyer is...

  • Associate Director, QA GCP/PV

    6 maanden geleden

    Utrecht, Nederland Genmab Voltijd

    At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...

  • Associate Director Holdings Controller

    6 maanden geleden

    Utrecht, Nederland Bristol Myers Squibb Voltijd

    Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms...

  • Associate Director, Transfer Pricing

    3 weken geleden

    Utrecht, Nederland Genmab Voltijd

    At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...

  • (Associate) Director Portfolio Manager

    4 weken geleden

    Utrecht, Nederland Rabobank Voltijd

    **This is what we offer you** - Gross monthly salary between EUR 5,115 and EUR 7,308 (scale 10) for a 36 hour week - Thirteenth month's salary and 8% holiday allowance - 11% Employee Benefit Budget - EUR 1,400 development budget per year - Hybrid working: balance between home and office work (possible for most roles) - A pension, for which you can set the...

  • Director of Advanced Research Center for Nanolithography

    2 dagen geleden

    Utrecht, Nederland NWO-I Voltijd

    **Job description**: The Advanced Research Center for Nanolithography (ARCNL) is a unique public-private partnership established in 2014 by the Dutch Research Council NWO, the University of Amsterdam, the Vrije Universiteit Amsterdam and semiconductor equipment manufacturer ASML. In 2022, the University of Groningen joined as associate partner. ARCNL is...

  • Global Corporate Affairs Associate Director, Alzheimer’s disease

    5 maanden geleden

    Utrecht, Nederland Lilly Voltijd

    We’re looking for people who are determined to make life better for people around the world. The Associate Director of Corporate Affairs (CA) for Alzheimer's disease will play a crucial role in supporting both the development and implementation of international strategies to improve the detection, diagnosis, and care of Alzheimer's disease. Through a...

  • Associate Director, Fp&a

    2 maanden geleden

    Utrecht Binnenstad, Nederland Insmed EU Careers Voltijd

    Company Description: Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are...

  • Associate Director, Clinical Research Scientist

    6 maanden geleden

    Utrecht, Nederland Genmab Voltijd

    The Role This position serves as a key role in the effective implementation of the global development strategy leading or co-leading one or more clinical trials in a therapeutic area for one or more compounds in various stages of clinical development (including clinical trial implementation, and oversight of all aspects of clinical development) working...

  • Associate Director

    2 maanden geleden

    Utrecht, Nederland Virtusa Voltijd

    For a leading Dutch based bank, we are looking for a Data Analyst/Data Management Consultant within the Fin Crime domain This is a senior position where the applicant needs to have 10 plus years of domain consulting experience. Additionally the consultant needs to have Data management skills. The day to day work requirements involve Analyzing and translating...

  • (Associate) Director, Global Drug Safety

    6 maanden geleden

    Utrecht, Nederland Genmab Voltijd

    At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...

  • Clinical Associate Professor of Practice/ Clinical Assistant Professor of Practice

    6 maanden geleden

    Utrecht, Nederland HKU Voltijd

    HKUMed is now seeking exceptional candidates in the following disciplines to join its ranks: Anaesthesiology/ Cancer Medicine/ Clinical Oncology/ Community Medicine/ Critical Care Medicine/ Diagnostic Radiology/ Emergency Medicine/ Family Medicine and Primary Care/ HKU Health System/ Medical Oncology/ Medicine/ Microbiology/ Obstetrics and Gynaecology/...

  • Quality Assurance Associate

    2 maanden geleden

    Utrecht Oost, Nederland GenDx Voltijd

    **GenDx, experts in transplant diagnostics** GenDx is a global leader in molecular diagnostic laboratory solutions for high resolution tissue typing of both donors and patients and monitoring transplant success. We combine our cutting-edge software solutions, reagents for DNA sequencing-based HLA typing and Chimerism monitoring strategies with our excellent...

  • Associate Director, Translational Medicine

    6 maanden geleden

    Utrecht, Nederland Genmab Voltijd

    The Role The Associate Director, Translational Medicine (TM) is a member of the TM team, which is embedded in the global Translational Research & Precision Medicine Department. The TM team focuses on preclinical and clinical translational research to advance the clinical development of innovative and differentiated antibody therapeutics for the treatment of...

  • Payroll Expert

    4 weken geleden

    Utrecht, Utrecht, Nederland Genmab Voltijd

    About the RoleAs a seasoned Payroll Expert, you will play a pivotal role in managing the end-to-end payroll process for Genmab's Dutch entity. With approximately employees, you will be responsible for ensuring timely and accurate payroll resolutions, aligning with HROps and the payroll service provider on monthly and annual processes.Main Objectives and...

  • Tenure-Track Clinical Associate Professor/Clinical Assistant Professor

    6 maanden geleden

    Utrecht, Nederland HKU Voltijd

    HKUMed is now seeking exceptional candidates in the following disciplines to join its ranks: Anaesthesiology/ Cancer Medicine/ Clinical Oncology/ Community Medicine / Critical Care Medicine/ Diagnostic Radiology/ Emergency Medicine/ Family Medicine and Primary Care/ Medical Oncology/ Medicine/ Microbiology/ Obstetrics and Gynaecology/ Ophthalmology/...