Lab technician

7 maanden geleden

Amsterdam, Nederland Netherlands Cancer Institute Voltijd

Function description

The Netherlands Cancer Institute (NKI) is an independent research institute located in the lively city of Amsterdam. The Institute covers all major areas of molecular and cellular cancer biology, with special emphasis on mouse tumor models, immunology, functional screens, cancer cell biology and translational research. The Netherlands Cancer Institute and the Antoni van Leeuwenhoek Hospital form an integrated cancer center, combining a research laboratory and a hospital under one roof in a single, independent organization. All hospital departments have an extensive research program, often in close collaboration with the research laboratory. This research is focused on improving cancer treatment through imaging and molecular diagnostics, new medicine, immunotherapy, improved operating techniques, more effective radiotherapy, and combinations of these, epidemiology and psychosocial research.
The Akkari lab is seeking a talented and enthusiastic laboratory technician to support team members in investigating to the interaction between the tumor microenvironment and therapy resistance using mouse models of cancer

Lab technician –Tumor Biology and Immunology
 (full time, 36 hours/week)

Research assistant/technician position available starting in April 2024 in the group of Leila Akkari, Division of Tumor Biology and Immunology at the NKI (Amsterdam, NL) The appointment is for a minimum of 2 years.

Leila Akkari´s research group studies the microenvironment-mediated mechanisms of tumor maintenance and therapeutic resistance to conventional therapy in brain malignancies. In particular, we investigate the acquired resistance mechanisms resulting from alterations in the activation and recruitment of myeloid cells and their mediators in response to standard of care treatment in brain tumors, including radiotherapy, surgery and immunotherapy. Our research aims to identify the vulnerabilities in the cancer cell/ stromal compartment heterotypic communication in solid tumors that may be targeted therapeutically.

Our research interests involve the use of in vitro and in vivo systems for the study of brain cancer, including sophisticated imaging, as well as transgenic, cell-tracing mouse models and patients sample analyses.

The ultimate goal of our projects is to improve the understanding of the complexity of the tumor microenvironment to harness its potential, using the brain as an experimental settings of cancer inflammation.

Job requirements

We are looking for a talented and enthusiastic laboratory technician who is interested in a dynamic and ambitious environment at a top research institution. Her/his role will be to assist PhD students and post docs in their in vivo and in vitro work, while supporting the group organization and
The successful candidate must have, or be expecting, a technician training (type HLO) and be ale to work with animals (Article 9 or FELASA).
She/he will be able to effectively organize their time and demonstrable a pro-active personality and high ability to work in a group. Fluency in English and good communication skills are expected. Experience in immunological research areas, including flow cytometry and cell culture is a plus.

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