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Head of The Laboratory of Neuroendocrinology
3 maanden geleden
Head of the Laboratory of Neuroendocrinology: Leading translational research on pituitary, adrenal and neuroendocrine tumors in a worldwide highly acknowledged laboratory
- Reageer t/m
- WO
- Wetenschap en Onderzoek
- Reageer t/m
- Functie inhoud
Functie inhoud:
As head of the Laboratory of Neuroendocrinology you are in charge of the day-to-day coordination of the laboratory and supervision of translational studies on pituitary, adrenal and neuroendocrine tumors.
You supervise PhD students and laboratory technicians and collaborate closely with the clinical endocrinologists, the core facility multi-omics technology, bioinformaticians and the human disease models facility within the department of Internal Medicine.
You have the capacity to head several independent research lines on different endocrine tumor types and initiates studies in this field.
Finally, you contribute to the educational program for medical students.- Werkomgeving
Werkomgeving:
There is a close collaboration with the clinicians of the Division of Endocrinology with regard to clinical and translational studies based on the principle 'From bedside to bench and back'.
In addition, there is a close collaboration with the diagnostic laboratory of endocrinology.The department of Internal Medicine is subdivided in the divisions of Endocrinology, Vascular Medicine and Metbolic Disease, Nephrology, Immunology, Infectious Disease and Geriatrics.
Background
The Neuroendocrinology Laboratory has a long track record in translational research aiming to improve diagnosis and medical treatment opportunities for patients with (neuro)endocrine disorders, with focus on pituitary, adrenal and neuroendocrine tumors.
It is worldwide one of the few centers with extensive expertise on culturing endocrine tumor tissue.A tissue biobank has been set up and there is a close relationship with the clinic with access to unique patient cohorts.
In recent years, the Neuroendocrinology Laboratory has adopted multi-omics technology in order to accomplish a more thorough in-depth investigation of endocrine tumor tissue.
Transcriptomic, proteomic, epigenomic and microbiomic studies have been initiated in samples from adrenal, neuroendocrine tumors and also in modern 3D cell culture techniques.
Mission
The vision for the future of the Neuroendocrinology Laboratory is to further expand the multi-omics technology for the analysis of endocrine tumors and to further develop advanced tissue culturing techniques (3D cell culture, organ-on-a-chip) in order to:
- Unravel pathophysiological processes and tumor-microenvironment interaction.
- Identify molecular drivers of growth and hormonal production of endocrine tumors.
- Identify novel diagnostic, predictive and therapeutic biomarkers.
- Assess sensitivity for (new) drug therapy and screen for new therapeutic targets.
As such, the primary goal of our translational research is to develop personalized medical therapy for each patient by taking a patient to the lab and back approach.
- Profiel
Profiel:
You are expected to initiate, coordinate and supervise translational studies and PhD students in close collaboration with the clinical endocrinologists, the core facility multi-omics technology, bioinformaticians and the human disease models facility within the department of Internal Medicine.
You have the capacity to head several independent research lines on different endocrine tumor types and to head day-to-day coordination of a laboratory.
The following skills and qualifications are also required:
- PhD degree in a relevant discipline, an excellent track record and a strong translational research background in molecular and cellular tumor biology with appliedomics technology. Research experience in the field of pituitary, adrenal and/or neuroendocrine tumors is a plus.
- Proven ability in successfully obtaining research grants as principal investigator.
- Proven leadership skills and efficient management in a multidisciplinary environment.
- Fluent in spoken and written English
- Wat bieden wij
Wat bieden wij: - You will receive a contract for 1 year.
- The gross monthly salary amounts a maximum of € 8.555;
- Excellent fringe benefits, such as a 13th month that is already paid out in November and an individual travel expense package.
- Pension insurance with ABP, we take care of approximately 2/3 of the monthly contribution.
- Special benefits, such as an incompany physiotherapist and bicycle r
