Phd Position in Multiscale Spatiotemporal Modelling

7 dagen geleden

Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam Voltijd
Phd Position in Multiscale Spatiotemporal Modelling of Microbiome During the First 1000 Days of Life

Faculteit/Dienst:
Faculteit der Natuurw

, Wiskunde & Informatica
Opleidingsniveau:

Master
Functie type:
Promotieplaats
Sluitingsdatum:3 juli 2024
Vacaturenummer:13092- Are you driven by a desire to delve into the convergence of computational modelling, omics research, and exogenous factors as they relate to human health? Specifically, are you excited about utilizing computational science methods to investigate the impact of the human microbiome on health and disease?-
What are you going to do?

  • Model Development: Collaborate with an interdisciplinary team of researchers to integrate data from cohort studies, metabolomics analyses and in vitro experiments, to develop computational models relying on spatial modelling techniques such as cellular Potts and reactiondiffusion models that capture the interactions between the macroscopic changes in the host environment and the corresponding physical and biological changes in the microbiome.
  • Parameter Analysis: Analyse model parameters for interoperability (with other computational models) and interpretability using techniques such as complex network analysis and dimensionality reduction (ordination).
  • Intervention analysis: Develop qualitative and quantitative mathematical models to simulate the impact of lifestyle factors (e.g., nutrition, physical activity, sleep behaviour, cultural and environmental factors) on oral health and metabolic health outcomes. Use the simulation outcomes to propose intervention strategies.
  • Individual-Level Microbiome Wellness and

Immune Fitness Score:

Develop a method to arrive at an individual-level microbiome wellness and immune fitness score using the developed mathematical models.

For setting up the mathematical models and simulations, most programming will be in Python and/or C++.

What do you have to offer?

Your experience and profile Excellent English communication skills, both written and spoken, are necessary. A willingness to learn and observe wet-lab techniques, in order to better understand their use cases, limitations and potential for model validation, is highly valued.
Our offer

  • A temporary contract for 38 hours per week for the duration of 4 years (the initial contract will be for a period of 18 months and after satisfactory evaluation it will be extended for a total duration of 4 years). The preferred starting date is as soon as possible. This should lead to a dissertation (PhD thesis). We will draft an educational plan that includes attendance of courses and (international) meetings. We also expect you to assist in teaching undergraduates and master students.
  • Besides the salary and a vibrant and challenging environment at Science Park, we offer you multiple fringe benefits:
  • 232 holiday hours per year (based on fulltime) and extra holidays between Christmas and 1 January;
  • Multiple courses to follow from our Teaching and Learning Centre;
  • A complete educational program for PhD students;
  • Multiple courses on topics such as leadership for academic staff;
  • Multiple courses on topics such as time management, handling stress and an online learning platform with 100+ different courses;
  • 7 weeks birth leave (partner leave) with 100% salary;
  • Partly paid parental leave;
  • The possibility to set up a workplace at home;
  • A pension at ABP for which UvA pays two third part of the contribution;
  • The possibility to follow courses to learn Dutch;
  • Help with housing for a studio or small apartment when you're moving from abroad
    About us
  • The Faculty of Science (FNWI) has a student body of around 8,000, as well as 1,800 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain.
  • The mission of the Informatics Institute (IvI) is to perform curiositydriven and useinspired fundamental research in Computer Science. The main research themes are Artificial Intelligence, Computational Science and Systems and Network Engineering. Our research involves complex information systems at large, with a focus on collaborative, data driven, computational and intelligent systems, all with a strong interactive component.
    Any questions?
  • Do you have any questions, or do you require additional information? Please contact:
  • Applications should include the following information (all files apart from your CV should be submitted in one single pdf file):
  • detailed CV including the months (not just years) when referring to your education and work experience;
- a letter of motivation;

  • Your Master thesis (this can be in draft form if not yet finalised)

Please make sure to provide ALL requested documents mentioned above.

  • You can use the CV field to upload your resume as a separate pdf doc

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