Phd-student in Molecular Neuroscience

**Your function**: **Project**: Mechanisms of neuropeptide signaling in human brain** **Job description**: You will be part of international research networks and exploit a variety of other analysis tools available here. You will be appointed in Amsterdam and work primarily in Amsterdam with regular visits to the other labs. The PhD-students will be trained...

**Jouw functie**: **Project**: Decipher how mRNAs are captured at specific subcellular locations to support local translation in neurons **Project description**: Brain function requires precise regulation of the neuronal proteome, which involves localizing thousands of mRNAs to neurites for their translation at specific subcellular locations. The mechanisms...

**Location**:Amsterdam **Max hours per week**:38 **Salary**:€ 2.770 - € 3.539 **Duration of agreement**:4 years: first for 1 year, the employment contract will be extended in case of proper functioning **P**roject: Unlock the early-life pathological imprinting of Alzheimer's disease via lifestyle** The Neurogenesis & Neurodegeneration group (led by...

Two PhD Positions in Molecular Simulation of Nucleic Acids in the Marie Curie Network MeChaNiSM **Faculty/Services**:Faculty of Science**Educational level**:Master**Function type**:PhD position**Closing date**:01.02.2025**Vacancy number**:13566- Are you interested in the chemistry of DNA and do you enjoy working in an international and interdisciplinary...

**About the project**: The title of the project is: _In vitro_ human cortical microcircuits to advance stem cell-based precision medicine for neurodevelopmental disorders. Monogenetic neurodevelopmental disorders (mNDDs) affect about 1 in 6 children in the EU for which currently no general effective therapy exists. This project is part of the ZonMW-open...

**Project description**: The goal of this internship project is to obtain a molecular understanding of biomarkers for psychiatric symptoms. In a close collaboration between the Kole group (led by Prof. Maarten Kole), Huitinga group (led by Prof. Inge Huitinga) and the department of Psychiatry at the Amsterdam UMC (psychiatrist Karel Scheepstra), we are...

**About the project**: **Diffuse Large B cell Lymphoma (DLBCL) **is the most common aggressive (fast-growing) Non-Hodgkin-lymphoma with heterogeneous clinical outcome and molecular characteristics. Despite being an aggressive lymphoma, DLBCL is considered potentially curable. Unfortunately, a large proportion of patients do not benefit from standard...

**Jouw functie**: More than a quarter of global greenhouse gas emissions come from the food production chain. Replacing animal proteins in our diets with plant-based alternatives should drastically reduce these emissions. Plant-based diets are also healthier. However, current plant-based alternatives to dairy and meat do not have the desired taste, texture...

**Location**:Amsterdam **Max hours per week**:38 **Max salary**:5090,00 **Duration of agreement**:1 - 3 years **Postdoc in social rodent neuroscience: understanding social and brain dynamics of multiple individuals** Both human and rodents live in complex environments that include the necessity to interact with other conspecifics. To better understand...

**About the role**: To achieve our vision, we seek an ambitious PI to help shape the future of our neuropathology group and conduct cutting edge neuropathology-related research. You will closely collaborate with and be mentored by experienced neuropathologists and scientists affiliated with the Amsterdam Neuroscience research institute, a joint venture of...

**About the project**: Research in the **Amsterdam Leukodystrophy Center** aims at improving insight into leukodystrophies and developing treatment. The disease **“Megalencephalic Leukoencephalopathy with subcortical Cysts”** (MLC) has been a major research focus since long. In MLC, the homeostasis of ions and water in the brain is disrupted due to a...

**Your function**: **Your duties** - map out existing literature and generate new ideas - co-design and implement new experiments - collect, analyze, and curate data - report on the findings in local meetings and inter(national) conferences - write several scientific articles and a PhD thesis - assist in (minor) teaching activities within the department -...

PhD in Computational Electrochemistry (ANION) **Faculty/Services**:Faculty of Science**Educational level**:Master**Function type**:PhD position**Closing date**:01.02.2025**Vacancy number**:13628- Probing ultra-fast processes and correlations in nanoelectrochemistry: bridging time scales with path sampling.- Join us!- This PhD project focuses on...

**Jouw functie**: **Your duties** - Culturing and differentiation of human renal and hepatic cell system, including induced pluripotent stem cell (iPSC) derived models - Toxicological evaluations of applied test compounds including viability assays, barrier function, mitochondrial activity, metabolism and transcriptomics, - Data analysis, including...

Max hours per week: 38.00 Max salary: 8.025 Apply until: 30-06-2024 Are you interested in developing an innovative research group through a combination of core and extramural funding to study the biological mechanisms underlying neuropsychiatric disorders? Would you enjoy working in close collaboration with other research groups in an exceptionally...

**Your function**: **Your duties** Your role will be to: - develop data analysis methods tailored to ODORWISE - formulate testable hypotheses on how to exploit biological mechanisms for the rational design of protein targets - validate the models through existing experiments and in collaboration with experimental partners - supervise M.Sc. research...

**Location**:Amsterdam **Max hours per week**:38 **Max salary**:5278,00 **Duration of agreement**:1 - 3 years **Postdoc in social rodent neuroscience: understanding social and brain dynamics of multiple individuals** Both human and rodents live in complex environments that include the necessity to interact with other conspecifics. To better understand how...

**PhD student: The real-time dynamics of single ribosomes**: **Work Activities**: **Questions -** According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation may well be essential to produce multi-protein complexes...

**Your function**: Within the context of the EU-funded Marie Skłodowska Curie Doctoral Network (DN) “MeChaNiSM” there are 15 fully funded open positions for PhD students in the field of nucleic acids chemistry and biophysics. One of those position is at the Vrije Universiteit Amsterdam. You will get the opportunity to: - be supervised by an expert in...

**PhD student: Single-molecule biophysics of the ubiquitin motor Cdc48/p97**: **Work Activities**: **Questions -** Ubiquitin is central to a broadly important regulatory system within cells, which controls anything from protein degradation to membrane remodeling and DNA replication regulation. Cdc48 performs these tasks by disassembling protein complexes,...