Intern - Analytical Chemistry - Pats

5 maanden geleden

Oss, Nederland MSD Voltijd

We are looking for a motivated fourth-year HBO bachelor or WO master student Analytical Chemistry Do you want to know what it's like to be part of one of the largest multinational companies in the pharmaceutical industry? We offer an internship opportunity within our PATS department where you will have the freedom and space for your own initiative.

**Intern - Analytical Chemistry - PATS Material Science and Characterization**

**Welcome to our team**
The PATS department (Material Science and Characterization group) is an essential hub in our organization. This department is focused on physicochemical analytics. The solid state characterization team of the PATS Material Science & Characterization department features many state of the art solid state characterization techniques (FTIR, XRPD, TGA, DSC, DVS, SEM, PSD) to investigate the properties of APIs used in veterinary healthcare. The project will be a great chance to gain experience within the pharmaceutical industry. The team works closely with other departments within the company to achieve the stated goals.

**Your internship assignment**
Active pharmaceutical ingredients (APIs) are often administered in a solid form; e.g., as a tablet or capsule. To achieve the desired bioavailability of the drug, its rate of dissolution is of great importance. The dissolution rate of a drug product can be affected by many parameters such as the particle size, temperature, pH, presence of excipients, stirring speed, etc. As a baseline, it is valuable to know the dissolution rate of the pure API itself, whilst eliminating as many external parameters as possible: the intrinsic dissolution rate. The intrinsic dissolution rate is defined as the rate of dissolution of a pure API when the surface area, stirring speed, pH and ionic strenth of the dissolution medium are kept constant.

The scope of this internship is to introduce intrinsic dissolution testing as an additional characterization tool for APIs. The department features a SOTAX dissolution instrument, and UV-Vis and HPLC instruments for the analysis of the data.

**Your responsibilities**
- Introduce intrinsic dissolution testing to the solid state characterization team in an informative presentation
- Perform initial dissolution tests and analyze the results with e.g., HPLC and UV-Vis
- Develop a general method for the sample preparation, execution and result interpretation of intrinsic dissolution testing
- Evaluate the results and suggest adjustments
- Providing a fresh perspective within the department: your opinion matters

The described tasks form the basic package and will often be performed independently after a proper training and learning period. These tasks may be supplemented with other projects and/or tasks on your own initiative or at the request of the organization.

**What is required**
- A 4th year bachelor (HBO) or master student in analytical chemistry
- You are trained to work safely and effectively in a laboratory environment
- You are enthusiastic about analytical characterization techniques for APIs in the pharmaceutical industry
- You have (some) knowledge about HPLC analysis and/or dissolution (preferred)
- You are searching for an internship where you have the freedom to take initiative
- You are available for a period of at least 4 - 6 months for 5 days a week.

**What we offer**

Interning at our company means working together with your team towards health in an international work environment. As an intern, you will have the opportunity to work closely with experts and learn from them. In addition, we offer:

- The chance to gain experience in the pharmaceutical industry
- An opportunity to showcase yourself for potential opportunities after your internship period
- A challenging and dynamic work environment with plenty of room for personal development and initiative
- Good guidance from an experienced specialist
- A gross monthly internship allowance of €500;
- based on a 40-hour workweek

**Animal Health Division**

Our Animal Health Division is a trusted global leader in animal healthcare. We are committed to preserving and improving the health, well-being, and performance of animals and the people who care for them. As a global team of professionals, we work together to make a positive difference in animal care and the world's food chain. We also have a deep sense of responsibility towards our customers, consumers, animals, society, and our planet.

By being dedicated to The Science of Healthier Animals®, we provide veterinarians, farmers, pet owners, and governments with one of the broadest ranges of animal health products, vaccines, and solutions and services for health management. Additionally, we deliver a comprehensive range of digitally connected identification, traceability, and monitoring products. We invest in dynamic and extensive R&D capabilities and a modern, global supply chain. We are present in more than 50 countries, and our products are available in approximatel

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