Phd Bioinformatics Student

1 week geleden


Amsterdam, Nederland Netherlands Cancer Institute Voltijd

**Function description**:
**Function Description**
The research group of Reuven Agami at the division of Oncogenomics at the Netherlands Cancer Institute in Amsterdam has recently uncovered a novel phenomenon in cancer termed “Sloppiness”. They showed that the tumor microenvironment enforces the production of aberrant proteins in cancer cells (Bartok et al., Nature 2021; Champagne et al., Molecular Cell 2022; Pataskar et al., Nature 2022; Yang., Molecular Cell 2024). In a project awarded by ERC-AdG-2024 for five years, the Agami group will characterize Sloppiness in cancer, investigate how it is regulated, study the impact of the resulting defective protein products on cell phenotype, and generate novel tools for cancer (immune)therapies. These research lines comprise the usage and development of several computational approaches in the field of genomics and proteomics. The lab is well-equipped with computational resources, including five powerful high-performance servers.
- **Responsibilities**Job requirements**:

- The Agami lab seeks to recruit an ambitious bioinformatics PhD student with a background in large-scale data analysis and a strong commitment to science.
1. Experience with analyzing genomic datasets.
- 2. Knowledge of analyzing proteomics datasets is a plus.
- 3. Proficient in R and at least one of the following programming languages: PERL and Python.
- 4. Experience with high-performance computing and proficiency in UNIX and BASH scripting.-
**Compensation**:

- The gross salary per month for our PhD will range from €3.523;
- to a maximum of €4.277;
- according to the standard PhD scales. The terms of employment will be in accordance with the Collective Labor Agreement for Hospitals. In addition you will receive a fixed end-of-year bonus (8,33%) and you will receive 8,33% holiday pay.
- Your travel expenses will be reimbursed at € 0,19 per km. Free parking at the Antoni van Leeuwenhoek is also part of the package. Personnel is stimulated to use public transport and bicycle and therefore we offer an interesting arrangement for bikers and/or discount on the NS-business card.
- **Interested?**
- Applications should include your CV, a motivation letter and references.
- The NKI values diversity and is committed to creating an inclusive work environment that stimulates the best in each individual. Applications of all individuals are welcomed regardless of age, ancestry, religion, disability, distance from the labor market, sexual orientation or gender identity._

**Details**:

- Hours per week: 36
- Salary level: OIO

**Mylene van der Velden**:
**Reuven Agami**: Group leader



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