Postdoctoral Researcher: Automated Detection of RiPP Structural Features

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Leiden, Zuid-Holland, Nederland Universiteit Leiden Voltijd

We are seeking a highly motivated Postdoctoral Researcher to join our team at the Institute for Biology Leiden (IBL) to work on the development of algorithms for the automated detection of characteristic RiPP structural features in the microbial metabolome.

The successful candidate will be responsible for cataloging the different classes of RiPPs identified with LC-MS/MS, developing algorithms that detect the MS/MS fragmentation patterns specific to the different RiPP classes and PTMs, testing the generated algorithms on both in-house and publicly available MS/MS data, and implementing the new algorithms into existing software tools such as FERMO.

The ideal candidate will have a PhD in computational metabolomics or a related field, strong knowledge in organic chemistry and mass spectrometry, and experience in MS-based metabolomics data analysis and machine learning algorithms. Additionally, proficiency in spoken and written English, as well as excellent communication skills and a collaborative attitude, are essential.

The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry, and bio-pharmaceutical sciences to biology and environmental sciences.

The Institute for Biology Leiden (IBL) aims to work on the science base of biodiversity and health, reflected in our leading principle Harnessing Biodiversity for Health. We perform innovative curiosity-driven research to answer fundamental questions and solutions-driven research to help solve major societal challenges.

We offer a full-time, 2-year term position with a salary range from € 3,345,- to € 5,278,- gross per month (pay scale 10 in accordance with the Collective Labour Agreement for Dutch Universities). Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3%), training and career development, and sabbatical leave.

Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.



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