Computer-Aided Drug Design Researcher

3 weken geleden

Amsterdam, Noord-Holland, Nederland Vrije Universiteit Amsterdam Voltijd
Job Description

We are seeking an Assistant Professor to lead the Computer-Aided Drug Design (CADD) group within the Medicinal Chemistry division. The successful candidate will develop methodologies in molecular modeling, data management and machine learning to advance the understanding of ligand-protein interactions.

The candidate will have a background in drug development, medicinal chemistry, and computational chemistry, and will support research on G-Protein Coupled Receptors and Fragment-Based Drug Discovery. The role requires expertise in both ligand-based and structure-based drug discovery, and the molecular insights obtained will help guiding synthetic chemists and molecular pharmacologists through interdisciplinary collaboration within the division.

Responsibilities
  • Develop and apply a wide variety of computational techniques, including protein structure predictions, molecular dynamics, docking, virtual screening, structural chemogenomics, machine learning, AI, free-energy perturbations, etc.
  • Manage and analyze large datasets, with expertise in cheminformatics and bioinformatics.
  • Model G-protein coupled receptors and enzymes, and develop novel methodologies for drug discovery.
  • Program and script in various languages, and have a strong publication record.
  • Communicate effectively with colleagues and students, and have leadership skills to lead the CADD group.
Requirements
  • PhD in computational chemistry, medicinal chemistry, or a related field.
  • Experience in drug development, medicinal chemistry, and computational chemistry.
  • Strong publication record and leadership skills.
  • Ability to motivate and teach graduate and undergraduate students.
What We Offer
  • A challenging position in a socially engaged organisation.
  • A salary of minimum € 4.332,00 (Scale 11) and maximum € 6.737,00 (Scale 12) gross per month, on a full-time basis.
  • A position for at least 1 FTE, with a prospect of a permanent contract.

We are committed to creating an inclusive community, and believe that diversity and internationalisation contribute to the quality of education, research and our services. We are always searching for people whose backgrounds and experience contribute to the diversity of the VU community.

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