Neuroscience Researcher

4 weken geleden


Amsterdam, Noord-Holland, Nederland VU Amsterdam Voltijd

Project Overview

Project Title: Investigating Nanoscale Molecular Processes at Synapses

Project Description:

Synaptic plasticity, the ability to modify synaptic strength in response to neuronal activity, plays a crucial role in memory formation. This project aims to understand the molecular events that induce long-term alterations in synaptic structure and function. Recent super-resolution microscopy studies have revealed an exciting new level of nano-structural plasticity relevant for memory formation. However, the molecular processes that coordinate these processes remain unresolved. In this project, you will investigate how nanoscale molecular processes at synapses control memory formation using CRISPR/Cas9-based tools, super-resolution microscopy, optogenetics, and electrophysiology.

Your Responsibilities

  • Investigate the molecular processes that control synapse nanostructure and function using various techniques.
  • Perform and analyze microscopy and electrophysiology data.
  • Publish in peer-reviewed journals and provide progress reports to funding sources.
  • Contribute to teaching activities, including supervision of BSc and/or MSc students during internships.
  • Present your work to the international research community.

Requirements

  • A Master degree in life sciences, biomedical sciences, or biophysics with neuroscience specialization.
  • Hands-on experience with molecular and cellular neuroscience, preferably with molecular biology, (live-cell) fluorescence microscopy, and/or electrophysiology.
  • Hands-on experience with imaging and/or bioinformatics is an advantage.
  • Fluency in English (written and spoken) and good communication skills.

What We Offer

  • A challenging position in a socially engaged organization.
  • A salary of € 2,000 (PhD) and maximum € 3,000 (PhD) gross per month in the fourth year, for a full-time employment.
  • An employment contract of initially 1 year, extendable to a total of 4 years.

Benefits

  • A full-time 38-hour working week comes with a holiday leave entitlement of hours per year.
  • 8% holiday allowance and 8.3% end-of-year bonus.
  • Optional model for designing a personalized benefits package.
  • Contribution to commuting expenses.
  • A wide range of sports facilities which staff may use at a modest charge.


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