Postdoc Researcher in Liver Models for Toxicity Testing

4 dagen geleden

Amsterdam, Nederland VU Amsterdam Voltijd

Your function

We are looking for a motivated Postdoc with a strong background in advanced human cell culture systems, including organoids, and in molecular toxicology.



Your duties



Development of induced pluripotent stem cell (iPSC)-derived liver models, including organoids derived of hepatocytes and non-parenchymal cellsCharacterisation of functional phase I and II metabolismData analysis and integration of several toxicology assays, including Seahorse bioanalyser (mitochondria toxicity) and transcriptomics datasetsHigh Content ImagingPublish scientific articles and present research results at conferences;Supervision of MSc and BSc students and co-supervision of PhD candidatesCollaborate within the team and with other international researchers

Your profile

PhD obtained within the last 5 years within the discipline of either toxicology, pharmacology, cell -or developmental-biology or a related discipline;Strong expertise in 3D human cell culture and iPSC, ideally with liver modelsBackground in toxicology and mechanistic assaysAptitude for data handling and analysis; Transcriptomics analysis is a plusExperience with analytical methods (LC-MS) is an advantageGood communication, organizational and social skills;High proficiency in speaking and writing in the English language;Team player with the ability to work independently;Strong motivation for scientific research

As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.



We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements.


What do we offer?

A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:



a salary of minimum € 3.,00 (Scale 10) and maximum € 5.,00 (Scale 10) gross per month, on a full-time basis. This is based on UFO profile Researcher 4. The exact salary depends on your education and experience.a position for at least 0.8 FTE. Your employment contract will initially last 1 year.

We also offer you attractive fringe benefits and regulations. Some examples:



A full-time 38-hour working week comes with a holiday leave entitlement of hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.8% holiday allowance and 8.3% end-of-year bonusspace for personal developmenta wide range of sports facilities which staff may use at a modest chargediscount on (and occasionally exclusive access to) theater performances and courses at the Griffioen Cultural Center

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