Huidige banen gerelateerd aan PhD Position - Groningen - Universitair Medisch Centrum Groningen

  • Phd Position

    3 maanden geleden


    Groningen, Nederland UMCG Voltijd

    **Functiebeschrijving**: The project is a continuation of ongoing research into the dysregulation of immune tolerance in AAV, particularly concerning the role of Tregs. AAV are rare, chronic, relapsing autoimmune diseases characterized by inflammation of small blood vessels, commonly affecting the kidneys, lungs, and upper airways. Dysregulation of immune...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking a highly motivated and talented PhD candidate to join our research team in the Department of Medicinal Chemistry, Photopharmacology and Imaging at the Groningen Research Institute of Pharmacy, Faculty of Science and Engineering, University of Groningen.Project OverviewThis project is part of an ERC-funded consortium that aims to...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking a highly motivated PhD candidate to join our research team at the Groningen Research Institute of Pharmacy, University of Groningen. The successful candidate will be part of an ERC-funded consortium that aims to develop new light-activated molecules for protein transport substrates.Key ResponsibilitiesDesign, synthesize, and...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking highly motivated and enthusiastic PhD candidates to join our Systems Biology of Predatory Bacteria group at the Rijksuniversiteit Groningen. Our research focuses on understanding the life cycle of the bacterial predator Bdellovibrio bacteriovorus and its interactions with prey bacteria.Research FocusOur group uses systems...

  • Phd Position

    3 maanden geleden


    Groningen, Nederland UMCG Voltijd

    **Functiebeschrijving**: The project will be focused on: 1) material science for developing strategies for efficient EVs retention into a protein-based hydrogel system; 2) study of the mechano-structural properties of the target tissue for designing promising architectures for bioprinting; 3) bioprinting technology for manufacturing constructs with refined...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking highly motivated PhD candidates to join our research team at the University of Groningen. The successful applicants will be part of a collaborative project between the research groups of Dr. Ruben Bierings and Dr. Geert van den Bogaart, focusing on the identification of organelle trafficking routes responsible for Weibel-Palade...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    About the PhD PositionThe Graduate School of the Faculty of Economics and Business at the University of Groningen is seeking a highly motivated PhD candidate to conduct research on the relational drivers of audit quality. The successful candidate will join a collaborative and supportive team with a proven track record in consulting, auditing, and...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking highly motivated and enthusiastic PhD candidates to join our Systems Biology of Predatory Bacteria group at the Rijksuniversiteit Groningen. Our research focuses on understanding the life cycle of the bacterial predator Bdellovibrio bacteriovorus and its interactions with prey bacteria.Research FocusOur group uses systems...


  • Groningen, Nederland University of Groningen Voltijd

    Job description We are looking for a PhD candidate in the group of Prof. A. J. Minnaard, who leads a natural product synthesis group at the Stratingh Institute for Chemistry (see: minnaardgroup.nl). Within the framework of his Ammodo Science Award, the position focusses on the total synthesis of membrane components of M. tuberculosis. In an ongoing...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    About the PhD PositionThe Graduate School of the Faculty of Economics and Business at the University of Groningen invites applications for a fully funded PhD position on the topic "Relational Drivers of Audit Quality: Studying the Behavioral Dynamics Between Auditors and Upper Echelon Actors".Research FocusThis PhD project aims to identify how relational...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    About the PhD PositionThe Graduate School of the Faculty of Economics and Business at the University of Groningen invites applications for a fully funded PhD position on the topic of relational drivers of audit quality. This research project aims to investigate how relational dynamics between auditors and upper echelon actors shape audit quality.Research...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionAt the Groningen Research Institute of Pharmacy, we are seeking a highly motivated PhD candidate to join our team in the field of nanomedicine for intestinal fibrosis associated with inflammatory bowel diseases (IBD).The successful candidate will be part of a multidisciplinary research project that aims to develop innovative cell-selective...

  • PhD Position in Biophysics

    1 maand geleden


    Groningen, Nederland University of Groningen Voltijd

    Job description The Heinemann Lab at the University of Groningen (Netherlands) aims to understand how cellular metabolism functions and how metabolism controls other cellular processes. The lab has recently found that cellular metabolism does not operate beyond a certain Gibbs energy dissipation rate (Niebel et al, 2019, Nature Metabolism). This observation...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    About the PhD PositionThe Rijksuniversiteit Groningen is seeking a highly motivated PhD candidate to join its research team in the Faculty of Economics and Business. The successful candidate will be part of a fully funded PhD project focused on the relational drivers of audit quality.Research ObjectivesThe PhD project aims to investigate how relational...

  • PhD position Photopharmacology

    4 maanden geleden


    Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job description Without biological membranes, there would be no life as we know it. Transport of molecules and information across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins...


  • Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Within the Chair Group of Economic and Social History, Faculty of Arts at the University of Groningen, the Netherlands, a fully funded PhD position is currently available. The position will be within the ERC-funded project “Coping with decline: Comparative social-historical analysis of depopulation and community welfare in Europe, 1950-2022...


  • Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Belonging to the best research universities of Europe and joining forces with prestigious partner universities and networks, the University of Groningen is truly...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionWe are seeking highly motivated PhD candidates to join our research team at the University of Groningen, in collaboration with the Erasmus MC, Rotterdam. Our project focuses on understanding the organelle trafficking routes responsible for Weibel-Palade body (WPB) formation and secretion.Research ObjectivesThe successful candidates will...


  • Groningen, Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job DescriptionAt the Groningen Research Institute of Pharmacy, we are seeking a highly motivated PhD candidate to join our team in the field of nanomedicine for intestinal fibrosis associated with inflammatory bowel diseases (IBD).The successful candidate will be part of a multidisciplinary research project that aims to develop innovative cell-selective...


  • Groningen, Nederland Rijksuniversiteit Groningen Voltijd

    Job description Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Belonging to the best research universities of Europe and joining forces with prestigious partner universities and networks, the University...

PhD Position

4 maanden geleden


Groningen, Nederland Universitair Medisch Centrum Groningen Voltijd

PhD Position in Bioactive Materials, Bioprinting Technology and Tissue Engineering: Bioprinting of human extracellular vesicles for tissue engineering applications. Job description

Extracellular vesicles (EVs) have emerged as powerful nanoparticles for tissue engineering due to their cargo of proteins, lipids, and genetic materials, with remarkable non-immunogenic and regenerative potential. The use of EVs has proven to be translatable to clinical trials, for example for knee osteoarthritis and bone tissue defects. However, a major challenge of the use of EVs for implants that is impairing its progress is the difficulty of EVs to be retained in the target tissue. To solve this problem, EVs have been encapsulated in injectable hydrogels to achieve increased local site retention and slower release. Yet, the lack of defined structure and porosity are weakening the EV functionality. To overcome these limitations, bioprinting of EV-based hydrogels with refined control on tissue architecture holds advantageous features. Just a few published studies have investigated the use of 3D bioprinted-EVs for tissue engineering applications and this is the core of this PhD project.

The project will be focused on: 1) material science for developing strategies for efficient EVs retention into a protein-based hydrogel system; 2) study of the mechano-structural properties of the target tissue for designing promising architectures for bioprinting; 3) bioprinting technology for manufacturing constructs with refined control on tissue architecture, while establishing gradients of EVs and microenvironments for EVs retention; 4) long cell culture experiments for allowing the EVs actuation on cells after bioprinting; and 5) Mechanical and biological evaluation of the constructs regarding safety, effectiveness, immunomodulation and tissue regeneration.

This PhD project is part of the Biofabrication & Bioprinting Lab (BBT/UMCG) mission, that is, to pave the way for bioprinting of human EVs for opening a new era of medical implants. Working environment

The site of your research will be the Department of Biomaterials and Biomedical Technology (BBT/UMCG) with excellent guidance and facilities for scientific staff.The project will be carried out as part of an international and interdisciplinary team in a creative and collaborative research environment under supervision of dr. Monize Caiado Decarli at the department of Biomaterials & Biomedical Technology (BBT), based at the renowned University Medical Center Groningen (UMCG) and the University of Groningen (RuG). What do we need

Our team is searching for a creative and highly motivated PhD candidate eager to learn new topics and tools and to navigate across disciplines in a multidisciplinary field. We seek an enthusiastic PhD student who will push developments in the field, develop scientific independence, and supervise B.Sc. and M.Sc. students.

In addition, you need:

Bachelor and Master’s degrees in chemical/ mechanical/ bioprocess/ biotechnology/ biomedical engineering degrees or equivalent. Demonstrable research experience in material technology, design, and manufacturing techniques. The candidate must have experience in more than one of the above-mentioned topics. Demonstrable research experience in cell culture. Knowledge on the role of human proteins and EVs in the context of hydrogel development based on these bioactive compounds. Excellent command of written and spoken English. Proactivity, well-developed communication, and skills for working effectively in collaboration with colleagues in a team.

We are looking forward for you to joining our team

The UMCG has a preventive Hepatitis B policy. The UMCG can provide you with the vaccination, should it be required for your position. In case of specific professions a ‘Certificate of Good Conduct’ is required. What do we offer

We offer 1 fulltime PhD position within the Department of Biomaterials and Biomedical Technology (BBT/UMCG). The position is for four years. However, you will get a fulltime contract for 1 year, which will be extended for 3 years after positive evaluation. Extension of the contract will be based on sufficient progress and the expectation of a successful completion of the Ph.D. project. The salary will be € 3.017,- gross per month in the first year up to a maximum of € 3.824,- gross per month in the 4th year (PhD salary scale), based on a full-time appointment. In addition, the UMCG offers 8% holiday pay, and 8.3% end-of-year bonus.