Post-doc On Data Science in Exercise and Health

5 dagen geleden

Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd

**Your function**:
We are seeking a motivated and innovative **Postdoctoral Researcher** with expertise in **data science and exercise
- **or muscle physiology** to join our cutting-edge research on post-COVID syndrome. This project focuses on unraveling the pathophysiology of **post-exertional malaise (PEM)** in post-COVID patients, with the ultimate goal of identifying diagnostic biomarkers and therapeutic strategies.

**Project Overview**

Post-COVID syndrome is a new disease characterized by fatigue, muscle pain, and PEM, which resembles **myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) (see our work PMID: 38177128)**. This interdisciplinary project combines advanced -omics techniques with muscle and exercise physiology to:

- Characterize **skeletal muscle** and **immune cell responses** to exercise
- Study the acute effects of exercise on **blood, immune responses, and the autonomic nervous system**

**Responsibilities**
- Perform data analysis of **various -omics** datasets from skeletal muscle and blood.
- Develop and implement bioinformatics pipelines to analyze large-scale data data.
- Integrate physiological data (e.g., heart rate variability) with molecular findings.
- Collaborate with experimental scientists, clinicians, and external partners on biomarker validation and hypothesis generation.
- Contribute to scientific dissemination through high-impact publications, conference presentations, and collaborative discussions.

**Your profile**:

- A Ph.D. in Human Movement Sciences, **Bioinformatics, Data Science **or related fields.
- Expertise in analyzing **-**omics data.
- Proficiency in programming languages (e.g., **R, Python**) and statistical methods for biological data analysis.
- Experience with machine learning and predictive modeling in biomarker discovery is an asset.
- Strong communication and collaboration skills to work in a multidisciplinary environment.
- You have excellent verbal and written English language skills
- A proven track record of peer-reviewed publications.

As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.

We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements.

**What do we offer?**:
A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:

- a salary of minimum € 3.345,00 (Scale 10) and maximum € 5.278,00 (Scale 10) gross per month, on a full-time basis. This is based on UFO profile Researcher 4. The exact salary depends on your education and experience.
- a position for 1 FTE. Your employment contract will last 24 months.

We also offer you attractive fringe benefits and regulations. Some examples:

- A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.
- 8% holiday allowance and 8.3% end-of-year bonus
- contribution to commuting expenses
- a wide range of sports facilities which staff may use at a modest charge
- optional model for designing a personalized benefits package

**About us**:
**About the team**
This post-COVID project is led by Dr Rob Wüst and is part of the Section Physiology at the Department of Human Movement Sciences at the Vrije Universiteit Amsterdam. The group is world-leading in its work on muscle physiology and responses to exercise, physical inactivity and in patients with post-COVID condition. Other scientific staff members include Prof Richard Jaspers, Dr Richie Goulding, and we work closely with clinicians treating post-COVID patients. The research group has expertise in skeletal muscle signaling, metabolism and function and uses techniques ranging from bioinformatics, (electron/immuno-fluorescence) imaging, biomedical laboratory techniques to whole-body exercise responses. The group values high quality research, personal development, and social cohesion within an international atmosphere. The lab consists of ~15 PhD students from all over the world. We have a bi-weekly lab meeting, a weekly team meeting, as well as regular social events.

**Faculty of Behavioural and Movement Sciences**
Developing knowledge for an active, healthy and meaningful life: that is our mission at the Faculty of Behavioural and Movement Sciences at VU Amsterdam. We maintain a broad focus on the fie

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