Scientist, Msat Lm Ds

3 maanden geleden


Leiden, Nederland Johnson & Johnson Voltijd

Johnson & Johnson is currently seeking a Scientist to join our Manufacturing Science and Technology (MSAT) Lab located in Leiden, the Netherlands.

We operate within the Large Molecule Drug Substance (LM DS) platform, which is a segment of the global MSAT organization.

As we work to enhance MSAT capabilities to fully own our current and future commercial products, we are establishing a dedicated MSAT LM DS Lab specializing in Large Molecules (mAbs, complex glycoproteins, bi
- & tri-specifics). This lab will house small-scale equipment including 2-10 L bioreactors (fed-batch and continuous perfusion), downstream processing and process analytical lab equipment.

The MSAT Lab will support Life Cycle Management of commercial products and Secondary Technology Transfers. Our lab will conduct satellite runs in Leiden and for EU & Row address complex investigations, process improvements, and serve as a non-routine sample hub.

You will be a key contributor to our team, playing a vital role in complex investigations and enhancing the robustness and reliability of upstream processes for large molecules in our global commercial portfolio. You will work independently, while receiving guidance and support from the Principal Scientist, to execute experiments, analyze data, and contribute to the advancement of key projects.

Key Responsibilities:

- Upstream Process Investigations & Optimization:

- Design, execute, and analyze experiments related to upstream processes of our commercial LM products.
- Contribute to the development and implementation of robust and scalable upstream processes (reduced scale models).
- Troubleshoot process challenges and identify potential improvements.
- Data Analysis & Reporting:

- Analyze experimental data independently and prepare thorough and scientifically sound reports.
- Effectively communicate results to partners and stakeholders.
- Technical Expertise & Innovation:

- Stay abreast of the latest advances and technologies in upstream process development.
- Contribute to the development and implementation of technical solutions to address manufacturing challenges.
- Collaboration & Communication:

- Work collaboratively with other members of the MSAT team (both local and global), sharing knowledge and expertise.
- Effectively communicate with colleagues and stakeholders, providing clear and concise updates on project progress.

**Qualifications**:

- Educational Background:

- Advanced degree (MSc/MBA/PhD) in a relevant field, such as Biochemistry, Biotechnology, Chemical Engineering, or a related field.
- Experience:

- 4+ years with advanced degree MSc/MBA/Ph.D. or equivalent
- OR 7+ years of relevant experience and Bachelor’s degree or equivalent
- Hands-on experience with cell culture techniques, bioreactor operation, and process optimization.
- Technical Skills:

- In-depth knowledge of upstream processes, including cell culture optimization, and bioreactor operation.
- Proficiency in data analysis and interpretation.
- Familiarity with regulatory guidelines and good manufacturing practices (GMP).
- Problem-Solving & Analytical Skills:

- Demonstrated ability to solve complex scientific and technical challenges independently and within a team setting.
- Strong analytical skills, with the ability to critically evaluate data and draw sound conclusions.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.


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