Bioinformatician - Erc-funded Project On

3 maanden geleden


Utrecht Oost, Nederland Prinses Máxima Centrum Voltijd

Are you a motivated bioinformatician and do you enjoy working in a diverse team? Do you want to contribute to the Princess Máxima Centre’s mission, to cure every child with cancer, with optimal quality of life? We would like to get in contact with you.

**The project**

As a bioinformatician in our group, your key responsibilities will include:

- Executing established pipelines for single-cell multi-omics (RNA, CITE-seq, single-cell WGS) and spatial transcriptomics datasets.
- Maintaining and optimizing analysis pipelines in line with the current state-of-the-art.
- Implementing novel data-analysis pipelines, particularly for spatial transcriptomics.
- Contributing to data interpretation and preparation of scientific manuscripts.
- Supporting researchers in storing, managing, archiving and sharing their research data.

**Profile**
- A Master’s degree in Life Sciences, Engineering, Computer Science, Information Systems, or equivalent.
- Demonstrated experience in bioinformatics.
- Familiarity with, or a desire and ability to learn, single-cell RNA sequencing analysis.
- Proficiency in programming languages such as R, Python and bash.
- A keen interest in translational childhood cancer research.
- Team player, who enjoys contributing to a multidisciplinary team.
- A desire to learn and adapt to new technologies and methodologies.

**Our job offer**

We offer a challenging position in an international, multidisciplinary research environment, which combines clinical oncology, stem cell biology and single-cell genomics. The position is based on 32 to 36 hours a week. You will initially be appointed for the duration of one year, with a possible extension. Your gross monthly salary will depend on your experience and background, starting in scale 55 with 8,33% gross monthly salary holiday allowance and 8,33 % end-of-year bonus. The Princess Máxima Center operates according to the collective labor agreement ‘cao algemene ziekenhuizen’. The starting date is flexible, with a target in Q1 of 2025.

**The Belderbos lab**

The Belderbos lab, established in 2020, focuses on translational hematopoietic stem cell biology. Our mission is to understand the fundamental mechanisms by which human hematopoietic stem cells regenerate blood and translate this knowledge into therapies to improve hematopoiesis in children with bone marrow failure, or in those undergoing stem cell transplantation. To achieve this mission, we employ a multidisciplinary approach, integrating single-cell technologies, in vitro assays and clinical studies in pediatric patients.

Our team consists of two postdocs, four PhD students, two wet-lab technicians and a bioinformatician. We closely collaborate with the single-cell genomics facility, with whom we have shared lab meetings, with clinicians and with several other (inter-)national research groups. Core values in our group include collaboration, curiosity and clinical impact. Our team is committed to fostering a supportive culture that encourages each team member to excel and contribute their unique talents.

**The Princess Máxima Center**

The Princess Máxima Center for Pediatric Oncology is an integrated hospital and research institute, which integrates healthcare, research and education on pediatric cancer, in a single location in Utrecht. Our institute aims to provide the highest level of care for all children with cancer, with optimal quality of life. The center brings together the best possible care and scientific research, creating a unique interdisciplinary institute for pediatric oncology in Europe.

**Contact**
- An up-to-date resume/CV
- A short motivation letter (maximum one A4)
- Contact information of 2-3 references

For more information about this position, or to arrange an informal chat, please contact Dr. Mirjam Belderbos. Mirjam will be happy to provide you with more information.
- Acquisitie naar aanleiding van deze vacature wordt niet op prijs gesteld._

**Details**:

- 32 - 36 hours per week
- FWG: 55
- Min. €3.606;
- max. €5.084,
- **Contactpersoon**:
Mirjam Belderbos


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