Phd Candidate: Evidence-driven Black-box Checking

4 years **_Are you looking for a PhD trajectory at our team? We are immediately looking for a talented and driven team member with a background in medicine or technical medicine who is interested in cutting-edge medical technologies. Within the interventional cardiology department of Radboudumc, we are motivated to improve patient care through the appliance...

The Department of Ophthalmology of the Radboud University Medical Center is a global leader in the field of multifactorial and genetic retinal eye diseases. The research of the department is focused on retinal forms of blindness that affect large numbers of patients worldwide, especially inherited retinal degenerations (IRDs), such as retinitis pigmentosa,...

The project aims to examine uni You will furthermore be trained in soft skills like scientific presentation, participation in various (inter)national conferences, and will contribute to outreach activities. As an obligatory part of the PhD trajectory at the Radboudumc and the Donders Institute for Brain, Cognition and Behaviour, you are required to write...

4 years **_We are looking for a talented PhD student who will join our research group ’_**_Strenghts, positive aspects and resilience in neurodevelopmental conditions_**_’ at the department of psychiatry. Within this research group we focus on investigating positive aspects and resilience in for example people with ADHD. We hope to provide a more...

4 years **_Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with the lowest 5-year survival among all solid tumors. Cancer-associated fibroblasts (CAFs) promote tumor cell proliferation and prevent chemotherapy and immune cells from attacking the tumor, leading to poor patient outcome. Novel approaches to kill these CAFs are therefore...

4 years **_Are you interested in unraveling the immunopathogenesis of endometriosis and whether lifestyle interventions can manage pain in endometriosis? Come join us as for this exciting PhD project._** Endometriosis is a hormone-dependent chronic inflammatory disease, affecting 6-10 % of women in reproductive age and as such it is one of the major causes...

A total knee arthroplasty (TKA) is a successful intervention for treatment of advanced knee osteoarthritis. But it does not provide a permanent solution for every patient, so revision surgeries will be needed. With the increasing numbers of implants placed, also the numbers of revision implants will increase. When taking out the primary implant for revision...

3 years **_Have you ever wondered why some cancers respond well to certain therapies and others do not? Tumours that develop as a result of BRCA1/2 deficiency are deficient in homologous recombination (HRD) and present a high level of genomic instability. The presence of HRD and related-genomic instability may guide treatment decisions for certain types of...

Blindness is among the top 15 most disabling conditions, and can manifest in many different ways. In young people, a hereditary retinal condition is the main cause, while age-related macular degeneration is the main cause in the elderly. The Lifelong VISION program is developing a new generation of treatment strategies to prevent blindness: genetic...

The Department of Ophthalmology of the Radboud University Medical Center is a global leader in the field of multifactorial and genetic retinal eye diseases. The research of the department is focused on retinal forms of blindness that affect large numbers of patients worldwide, especially inherited retinal degenerations (IRDs), such as retinitis pigmentosa,...

4 years **_Prof.dr. Carolina de Weerth (Developmental Psychobiology Lab; Radboud University Medical Center) is looking for a PhD within the project Nurturing Connections: The Role of Physical Closeness in Parent-Infant Well-being and Development. This 4-year project (1.0FTE) is financed by NWO and focused on early parenthood and infancy. Do you want to take...

Bladder cancer is in the top ten of most common cancers in the world; in the Netherlands, each year almost 7,000 people are diagnosed with bladder cancer. Our group aims to tackle unmet needs in the treatment of bladder cancer by use of epidemiological research. We are specialized in genetic epidemiological studies, but also study non-germline...

Colorectal cancer (CRC) is the third most common cancer worldwide, with rising incidence rates. Recent studies have revealed that bacterial oncotoxins—carcinogenic compounds produced by gut bacteria—may play a significant role in CRC development. This project funded by the Dutch Digestive Diseases Foundation (MLDS), led by Dr. Annemarie Boleij at...

4 years **_Every day, clinics worldwide generate vast amounts of digital data on healthy and diseased individuals. Digital pathology alone, with its high-resolution imaging of tissue samples, provides wealth of large-scale data that can contribute to improved understanding of disease morphology and tissue phenotype, potentially providing new insights to help...

4 years **_Cancer continues to be a major public health and economic burden, with 19.3 million new cases and 10 million deaths worldwide in 2020. As the global population ages, the incidence and mortality from cancer are expected to rise by 47% to 28.4 million new cases by 2040. Medical imaging, including CT and MRI scans, is critical in the management of...

The project is a continuation of an ongoing collaboration on Bayesian Federated Inference and Survival Analysis between the two sections. In research into rare diseases only small data sets are typically available. When using such small data sets for prediction, the risk of overfitting in the models used is high. This limits severely the ability to infer...

We are seeking an experienced Culinary Innovation Director to lead our International Consumer & Culinary Experience team. The successful candidate will drive culinary excellence and innovation across our global markets, working closely with passionate culinary chefs and consumer scientists.This role is ideal for a seasoned professional with 4+ years of...

We are seeking an experienced Steel Cladding Specialist to join our team in the Netherlands. This is a hands-on role that requires skill and precision, with a focus on installing various panels, including sandwich panels and back wall profiles.Key ResponsibilitiesMounting panels securely on roofs and façades using hand and power toolsCutting and fitting...

The position will become available in the first quarter of 2025 (1.0 fulltime equivalent; 4.0 years) and will lead to a PhD thesis. Neuronal cells in the brain are organized in physically connected functional networks. Proper functioning of these networks requires coupling in time and space of neuronal electrical activity, energy metabolism and redox...

In radionuclide therapy, a tumor-targeting vector is coupled to a therapeutic radionuclide to specifically irradiate tumor lesions from inside the body. This approach allows for the delivery of a high radiation absorbed dose to (metastasized) tumor lesions, while sparing healthy tissues. Despite the high potential of treatment, we currently do not know which...