Senior Antibody Research Scientist for Cancer Treatment

1 maand geleden


Utrecht, Utrecht, Nederland Genmab Voltijd
Company Overview

Genmab is an international biotechnology company with a core purpose guiding its unstoppable team to strive towards improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, its passionate, innovative and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates.

Job Description

As a Senior Antibody Research Scientist, you will play a key role in developing oligomeric protein targets and benchmarking their in vitro behavior, contributing to a better understanding of how the oligomeric state of a target influences antibody binding. This knowledge is expected to improve the screening and characterization of therapeutic antibodies and enable more efficient mapping of antibody binding characteristics.

Responsibilities:
  • Design proteins that constitutively exist in a certain oligomeric state using protein engineering techniques.
  • Support successful production and purification of these constructs.
  • Develop binding assays and perform affinity measurements using SPR and ITC.
  • Critically assess the quality and outcome of binding assays and provide the team with detailed molecular hypotheses underpinning the observed behavior.
Requirements

To be considered for this position, you should have a Master's degree in a relevant area, such as biomedical sciences or biomedical engineering, molecular biology, life sciences, immunology, or similar. You should also have knowledge and understanding of protein engineering and biophysical techniques such as ITC, SPR, and BLI.

About Genmab

Genmab is committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information.

Estimated Salary: €55,000 - €65,000 per year, depending on experience and qualifications. Benefits include a dynamic work environment, opportunities for professional growth and development, and a competitive salary package.



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