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Groningen, Groningen, Nederland Rijksuniversiteit Groningen VoltijdJob DescriptionWe are seeking a highly motivated PhD candidate to join our research team at the University of Groningen. The successful candidate will be part of the Integrated Research on Energy, Environment and Society group (IREES) within the Energy and Sustainability Research Institute Groningen (ESRIG).The PhD project will focus on the demand management...
PhD Position in Cellular and Molecular Neurobiology
2 maanden geleden
We are seeking a highly motivated and talented researcher to join our team at the University Medical Center Groningen (UMCG) to investigate the role of astrocytes in multiple sclerosis (MS) lesion progression. The successful candidate will have a Master's degree in Biomedical Sciences, (Cell) Biology or Neuroscience and a strong scientific drive.
Key Responsibilities- Conduct research on iPSC-derived astrocytes to reveal their functional differences from injury-naïve normal and MS sibling astrocytes.
- Investigate the response of astrocytes to inflammatory factors present in MS lesions and their impact on remyelination.
- Develop and apply various techniques, including human iPSC-derived glial and neuron cultures, morphometrics, RNA-sequencing analysis, proteomics, CRISPRa/i, and confocal microscopy.
- Contribute to a better understanding of MS and identify astrocyte-specific targets for novel therapeutic strategies.
- Master's degree in Biomedical Sciences, (Cell) Biology or Neuroscience.
- Strong scientific drive and motivation.
- Team player mentality, pro-active, flexible, and result-driven attitude.
- Good oral and written skills in English.
- Experience with human iPSCs or one of the mentioned techniques is an advantage.
- A full-time PhD position for four years (36 hours/week).
- A minimum salary of € 2,901,- gross per month in the first year and a maximum of € 3,677,- gross per month in the final year.
- 8% holiday pay and 8.3% end-of-year bonus.
