Postdoctoral Researcher: Investigating the Real-Time Dynamics of Individual Ribosomes
3 weken geleden
The translation process is a fundamental aspect of life, and recent studies have revealed that ribosomes can cooperate to produce protein complexes. Our research aims to elucidate the underlying mechanisms of this cooperation, including the synchronization of translation activity, the role of mRNA secondary structures, and the folding of protein complexes. **Methodology**
We will use a combination of optical tweezers and single-molecule fluorescence to study the real-time dynamics of individual ribosomes. This cutting-edge technique allows us to detect changes in individual molecules at nanometer and millisecond resolution. Direct collaboration with our partners provides complementary genome-wide in-vivo data. **Objectives**
- Investigate the real-time dynamics of individual ribosomes using optical tweezers and single-molecule fluorescence
- Elucidate the underlying mechanisms of ribosome cooperation, including synchronization of translation activity and mRNA secondary structures
- Study the folding of protein complexes and the role of chaperones in guiding this process
**Requirements**
We are seeking a highly motivated and experienced Postdoctoral Researcher with a strong background in single-molecule biophysics, programming skills, and a passion for collaborative research. Excellent verbal and written English skills are essential. **What We Offer**
- A dynamic and supportive research environment with access to state-of-the-art facilities
- Opportunities for professional development and collaboration with international research groups
- A competitive salary and benefits package
**How to Apply**
Interested candidates should submit their application, including a CV, a motivation letter, and contact information for at least two references, to https://www.amolf.nl/en/vacatures/. We are committed to diversity and inclusion and welcome applications from candidates from diverse backgrounds. AMOLF is an equal opportunities employer.
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Amsterdam, Noord-Holland, Nederland AMOLF VoltijdJob DescriptionThe successful candidate will join a dynamic research group at AMOLF to work on a project aiming to elucidate the real-time dynamics of single ribosomes. The researcher will use advanced biophysical techniques, such as optical tweezers and single-molecule fluorescence, to investigate the translation activity of individual ribosomes.Develop and...
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Postdoctoral Researcher: Investigating Single Ribosome Dynamics
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Amsterdam, Noord-Holland, Nederland AMOLF VoltijdJob DescriptionThe Postdoctoral Researcher will be part of a collaborative project at AMOLF, investigating the real-time dynamics of single ribosomes. The research involves using optical tweezers and single-molecule fluorescence to visualize the translation activity of ribosomes, their interactions, and the folding of individual polypeptide chains. The...
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Postdoctoral Researcher: Investigating Ribosome Dynamics
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