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Postdoctoral Researcher: Growing Cancer Organoids in Synthetic Matrices

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Nijmegen, Nederland Radboud University Voltijd

The ultimate goal is to establish a novel organoid platform for in vitro cancer modelling, personalised medicine and biobanking of patient-derived organoids for drug screenings or toxicology assays. As a proof of concept in this KWF-funded project, we aim to establish a PIC-based head and neck squamous cell cancer (HNSCC) ORGAnoid maTRIX platform, called ORGATRIX. 

This project is a close collaboration between Dr Paul Kouwer's group at Radboud University and Dr Marleen Ansems' group at the Radboud university medical center. As a postdoctoral researcher working on this project, you will be expected to work in both labs, which are conveniently located across the street from each other.

In the Kouwer Lab, you will prepare and modify PIC gels using protocols optimised for scientists without a strong materials chemistry background. Organoid cultures will be grown in these different PIC gels in the Ansems Lab. The team will hold biweekly meetings to exchange information, monitor progress and prioritise tasks.

A technician will be available to provide support in the cell biology experiments.