PhD in Cellular and Molecular Neurobiology

Alzheimer's disease (AD) is a progressive neurodegenerative disorder significantly influenced by immune system dysfunction. Understanding the underlying mechanisms and exploring avenues for the treatment of AD will be the goal of this position. A dysfunctional immune response may contribute to the development of AD. Based on our previous findings we...

The Heinemann Lab at the University of Groningen (Netherlands) aims to understand how cellular metabolism functions and how metabolism controls other cellular processes. The lab has recently found that cellular metabolism does not operate beyond a certain Gibbs energy dissipation rate (Niebel et al, 2019, Nature Metabolism). This observation could explain...

Von Willebrand Factor (VWF) plays a pivotal role in blood coagulation, with its secretion from Weibel-Palade bodies (WPBs) being essential for responding to vascular trauma. Dysfunctional WPB biogenesis and exocytosis are characteristic of bleeding disorders such as Von Willebrand disease. In this project, we aim to identify the organelle trafficking routes...

Job description We are looking for two highly motivated and enthusiastic PhD candidates with a strong background in microbiology, bioengineering, bioinformatics or closely related fields to join the Systems Biology of Predatory Bacteria group of Dr Renske van Raaphorst. The bacterial predator Bdellovibrio bacteriovorus has an unusual life cycle. When...

Job description Von Willebrand Factor (VWF) plays a pivotal role in blood coagulation, with its secretion from Weibel-Palade bodies (WPBs) being essential for responding to vascular trauma. Dysfunctional WPB biogenesis and exocytosis are characteristic of bleeding disorders such as Von Willebrand disease. In this project, we aim to identify the...

**Wat vragen wij**: We are looking for an ambitious, curious, and motivated PhD student with the following qualifications: - A university degree in bio-molecular sciences, medical biology or and relevant related area - An inquisitive mind - Communicative - A team player - Proficient in written and spoken English. - Experience with experimental research. -...

In an ongoing collaboration with tuberculosis-experts and molecular immunologists we identify and synthesize new components of the bacterial pathogen M. tuberculosis. These compounds have shown to be important for pathogenesis and virulence and are highly interesting from a molecular structure point of view. In parallel, we study how to translate fundamental...

**Functiebeschrijving**: The PhD student will work in close collaboration with collaborators at the University of Twente where novel sealants will be developed, to enable extensive testing of these compounds for toxicity and functionality using multiple in vitro and ex vivo lung cell and tissue culturing techniques at the UMCG. The PhD student needs to be a...

This 36 month PhD position is part of the European project Trans4Demo, which seeks to understand and respond to the challenges of populism for just sustainability transitions policy and liberal democratic values in Europe. The project will investigate the role and evolution of different forms of contentious politics (social movements and bottom-up...

**Functiebeschrijving**: **Wat vragen wij**: - A master's degree (or are close to graduating) in bioinformatics, statistical genetics, computational biology, molecular biology or a related field. - A good amount of experience and understanding of programming languages (Python and R are a big plus) and data analysis. - Experience working on a...

**Wat bieden wij**: Your salary will be a minimum of € 3.017; - gross per month in the first year and a maximum of € 3.824; - gross per month (scale PRO) in the final (4th) year, based on a full-time appointment. In addition, the UMCG will offer you 8% holiday pay, and 8.3% end-of-year bonus. The conditions of employment comply with the Collective...

Project Description The PhD researcher will work in the project ‘The roles of siblings and school peers in young adults’ life-course events’, led by Principal Investigator Clara H. Mulder and funded by an Open Competition Large grant from the Dutch Science Foundation (NWO). The research team will further include a postdoc researcher, an assistant...

The Centre for Media and Journalism Studies (CMJS) is looking for a PhD student in “Investigative journalism and interpretive “deep” reporting” within the HAICu research project. The HAICu project is a large-scale Dutch research project by universities and cultural-heritage institutions into new forms of Artificial Intelligence-based access to...

Job description Without biological membranes, there would be no life as we know it. Transport of molecules and information across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins...

Forgetting is a natural process that occurs in the life of every individual. In most cases it is functional and prevents the storage of unnecessary information. However, it can be maladaptive, for example in aging or pathological conditions such as in Alzheimer’s disease (AD). Despite the high burden of amnesia in the ever-growing elderly population and...

Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Belonging to the best research universities of Europe and joining forces with prestigious partner universities and networks, the University of Groningen is truly...

Our intricate social brain is implicated in a range of brain disorders, where social dysfunction emerges as a common neuropsychiatric feature cutting across diagnostic boundaries in anxiety disorders, major depressive disorders, Alzheimer’s disease and Schizophrenia. Understanding the underlying neurocircuitry mechanisms responsible for social dysfunction...

Responsibilities and tasks - Development of accelerated testing methods for testing SOFCs for trucking conditions. - Development of optically supported Accelerated stress testing methods. - Numerical and analytical cell performance modeling. - Cell level Accelerated Stress Testing. - Short stack level Accelerated Stress Testing. Organization The University...

Applications are invited for a fully-funded Postdoctoral researcher position for two years in the research group of Dr. Danny Incarnato, at the Groningen Biomolecular Sciences and Biotechnology Institute (GBB) of the University of Groningen (the Netherlands), to investigate RNA structural ensemble dynamics in living cells. What The successful applicant will...

The Wadden Sea is ‘the largest unbroken system of intertidal sand and mud flats in North western Europe. People living in the Wadden Sea area depend on the ecosystem services provided by a naturally dynamic and resilient ecosystem. At present, however, these characteristics are increasingly threatened by complex pressures of climate change, pollution,...