Phd Positions in Molecular Immunology

Job description Von Willebrand Factor (VWF) plays a pivotal role in blood coagulation, with its secretion from Weibel-Palade bodies (WPBs) being essential for responding to vascular trauma. Dysfunctional WPB biogenesis and exocytosis are characteristic of bleeding disorders such as Von Willebrand disease. In this project, we aim to identify the...

In an ongoing collaboration with tuberculosis-experts and molecular immunologists we identify and synthesize new components of the bacterial pathogen M. tuberculosis. These compounds have shown to be important for pathogenesis and virulence and are highly interesting from a molecular structure point of view. In parallel, we study how to translate fundamental...

**Wat vragen wij**: **Specific requirements**: - A PhD in immunology. - Strong affinity with human cellular immunology, specifically T cell immunology. - At least 2-3 years of postdoctoral experience. - Applicants with post-doctoral experience abroad are encouraged to apply. - Experience with primary cell cultures, functional immunological T-cell assays and...

Job description We are looking for two highly motivated and enthusiastic PhD candidates with a strong background in microbiology, bioengineering, bioinformatics or closely related fields to join the Systems Biology of Predatory Bacteria group of Dr Renske van Raaphorst. The bacterial predator Bdellovibrio bacteriovorus has an unusual life cycle. When...

The Heinemann Lab at the University of Groningen (Netherlands) aims to understand how cellular metabolism functions and how metabolism controls other cellular processes. The lab has recently found that cellular metabolism does not operate beyond a certain Gibbs energy dissipation rate (Niebel et al, 2019, Nature Metabolism). This observation could explain...

**Functiebeschrijving**: **Wat vragen wij**: - A master's degree (or are close to graduating) in bioinformatics, statistical genetics, computational biology, molecular biology or a related field. - A good amount of experience and understanding of programming languages (Python and R are a big plus) and data analysis. - Experience working on a...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder significantly influenced by immune system dysfunction. Understanding the underlying mechanisms and exploring avenues for the treatment of AD will be the goal of this position. A dysfunctional immune response may contribute to the development of AD. Based on our previous findings we...

Job description Without biological membranes, there would be no life as we know it. Transport of molecules and information across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins...

**Wat vragen wij**: We are looking for an ambitious, curious, and motivated PhD student with the following qualifications: - A university degree in bio-molecular sciences, medical biology or and relevant related area - An inquisitive mind - Communicative - A team player - Proficient in written and spoken English. - Experience with experimental research. -...

**Functiebeschrijving**: The project is a continuation of ongoing research into the dysregulation of immune tolerance in AAV, particularly concerning the role of Tregs. AAV are rare, chronic, relapsing autoimmune diseases characterized by inflammation of small blood vessels, commonly affecting the kidneys, lungs, and upper airways. Dysregulation of immune...

**Functiebeschrijving**: The PhD student will work in close collaboration with collaborators at the University of Twente where novel sealants will be developed, to enable extensive testing of these compounds for toxicity and functionality using multiple in vitro and ex vivo lung cell and tissue culturing techniques at the UMCG. The PhD student needs to be a...

**Functiebeschrijving**: The project will be focused on: 1) material science for developing strategies for efficient EVs retention into a protein-based hydrogel system; 2) study of the mechano-structural properties of the target tissue for designing promising architectures for bioprinting; 3) bioprinting technology for manufacturing constructs with refined...

Posted on December 14, 2023 Job description Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system characterized by neuroinflammation and neurodegeneration. Current disease-modifying therapies are non-curative and do not reverse progression. MS lesion progression is prevented by remyelination, a natural...

**Functiebeschrijving**: Stress is the ‘buzzword’ of modern life and impacts all aspects of daily life. When stress occurs frequently, remains high for sustained periods of time, and/or overwhelms people’s resources, it can cause mental and cardiometabolic disease. The NWO Gravitation project “Stress-in-Action” capitalizes on the fast advances in...

Within the Chair Group of Economic and Social History, Faculty of Arts at the University of Groningen, the Netherlands, a fully funded PhD position is currently available. The position will be within the ERC-funded project “Coping with decline: Comparative social-historical analysis of depopulation and community welfare in Europe, 1950-2022...

The PhD position is embedded in the research programme Economics, Econometrics and Finance of FEB’s Research Institute. The project will be supervised by Abe de Jong, in cooperation with Tim Kooijmans (RMIT) and Peter Koudijs (NYU). Organisation Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic...

Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Belonging to the best research universities of Europe and joining forces with prestigious partner universities and networks, the University of Groningen is truly...

Job description Intestinal fibrosis is a common complication in chronic inflammatory bowel diseases (IBD) like Crohn’s Disease and ulcerative colitis. It is a serious therapeutic problem, which is difficult to diagnose and treat. Intestinal tissue is easy to access with nanoparticles, which offers excellent opportunities for therapy and diagnosis...

The advent of modern artificial intelligence (AI) tools is accelerating scientific progress by streamlining research procedures across disciplines. Particularly, the release of ChatGPT showed the potential of large language models (LLM) to create detailed instructions based on textual prompts. Molecular simulations have the potential to greatly benefit from...

Responsibilities and tasks - Development of accelerated testing methods for testing SOFCs for trucking conditions. - Development of optically supported Accelerated stress testing methods. - Numerical and analytical cell performance modeling. - Cell level Accelerated Stress Testing. - Short stack level Accelerated Stress Testing. Organization The University...