Phd Position in Molecular Control of
6 maanden geleden
The immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate how plants control their growth during and after an immune response. This research is embedded in the CropXR work package on growth-resilience trade-offs and combines digital phenotyping and molecular omics technologies.
**Your job**:
Current projections show that the incidence of diseases on crops will increase in the coming decades, and thus, new strategies, beyond strengthening the immune system, are needed to ensure the resilience of future crops to diseases. It turns out that plants slow down their growth during and after an immune response regardless of the disease intensity. However, how these growth processes are regulated in plants is unclear. In this PhD project embedded in CropXR, you uncover the genetic and molecular basis of plant growth during and after an immune response. With this knowledge, we aim to develop solutions for resistance that do not compromise crop growth.
The project comprises three phases:
- In the first phase of the project, you will perform high-throughput digital phenotyping of _Arabidopsis thaliana_ mutant population grown with or without administered immunity-activating treatments in the Netherlands Plant Ecophenotyping Center (NPEC). You will utilise modelling, genetic mapping, and machine learning techniques to identify genes controlling the growth during and after an immune response.
- In the second phase of the project, validation of the genetic leads will be performed using CRISPR-Cas gene editing and alteration of gene expression.
A supervision team of 2-3 people will support your professional development as a researcher. Our research group and the CropXR consortium provide all the needed expertise. You will have opportunities to discuss your professional development and future career steps with a mentor from an industry or other area of your choice.
We currently have another PhD position on growth-immunity tradeoffs available in Dmitry Lapin’s team. For more information about this position, check out our website.
**Your qualities**:
We are looking for a collaborative, enthusiastic, and curious colleague who:
- has a completed MSc degree or is about to get an MSc degree in molecular and/or computational biology;
- has an affinity with experimental (plant) biology research;
- has demonstrated skills in either or both computational and molecular biology research;
- wants to learn, deploy, or even develop new methods of computational and molecular biology research.
**Our offer**:
We offer:
- a position for 4 years;
- a gross monthly salary between €2,770 and €3,539 in the case of full-time employment (salary scale P under the Collective Labour Agreement for Dutch Universities (CAO NU);
- 8% holiday pay and 8.3% year-end bonus;
- a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.
In addition to the terms of employment laid down in the CAO NU, Utrecht University has a number of schemes and facilities of its own for employees. This includes schemes facilitating professional development, leave schemes and schemes for sports and cultural activities, as well as discounts on software and other IT products. We also offer access to additional employee benefits through our Terms of Employment Options Model. In this way, we encourage our employees to continue to invest in their growth. For more information, please visit Working at Utrecht University.
**About us**:
A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. Sharing science, shaping tomorrow.
At the Faculty of Science there are 6 departments to make a fundamental connection with: Biology, Chemistry, Information and Computing Sciences, Mathematics, Pharmaceutical Sciences and Physics. Each of these is made up of distinct institutes that work together to focus on answering some of humanity’s most pressing challenges. More fundamental still are the individual research groups - the building blocks of our ambitious scientific projects.
The department of Biology consists of an Education Institute and 12 chair groups with a total of 350 staff members. The chair groups are organised within the Institute of Environmental Biology and the Institute for Biodynamics and Biocomplexity. The department is responsible for the Bachelor's programme in Biology, where we annually welcome over 400 students. This means we educate over 30% of biology students in the Netherlands. Additionally, staff members of the d
-
Phd Position in Molecular Control of
6 maanden geleden
Utrecht, Nederland Universiteit Utrecht VoltijdThe immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate the poorly understood process of how plants control their growth during and after...
-
Phd Position: Molecular Mechanisms of Protein
6 maanden geleden
Utrecht, Nederland Universiteit Utrecht Voltijd**Your job**: We are working at the interface of biochemistry, molecular biology and biophysics to follow the journey of nascent proteins toward their functional structures as they emerge from the ribosome. These mechanistic studies pave the way for targeted interventions against protein misfolding and perturbed protein homeostasis which are important for a...
-
Phd in Neuroscience
6 maanden geleden
Utrecht, Nederland UMC Utrecht VoltijdA PhD position for a period of 4 years on transcriptomically identifying distinct mouse neurons, and virally targeting them to modify behavior. Terms of employment in accordance with the CAO hospitals and UMCU salary scales.**Elke dag de zorg en de gezondheid van mensen verbeteren**Goede arbeidsvoorwaarden**Jezelf continu blijven ontwikkelen vinden we...
-
Phd Position: Exploring Microbial Potential for
7 maanden geleden
Utrecht, Nederland Universiteit Utrecht VoltijdPFAS (per - and polyfluoroalkyl substances) are so-called ‘’forever chemicals’’ that are found everywhere: in our soils, water, food and bodies. PFAS contamination of soils is an increasingly important global issue, and we still lack sustainable methods for PFAS remediate. The PFAS Remediation Living Lab is a contaminated location at the Utrecht...
-
Phd Position
2 maanden geleden
Utrecht, Nederland UMC Utrecht VoltijdWe offer a PhD position for 4 years in stem cell treatment in mouse models for Parkinson's Disease. Combining molecular, behavioral and in vivo neurophysiological approaches.**Elke dag de zorg en de gezondheid van mensen verbeteren**Goede arbeidsvoorwaarden**Jezelf continu blijven ontwikkelen vinden we belangrijk** **Dit ga je doen** The project focuses on...
-
Postdoctoral Researcher in Molecular Hematology
6 maanden geleden
Utrecht, Nederland Prinses Máxima Centrum VoltijdWe are seeking a highly motivated and talented Postdoctoral Researcher to join our team and contribute to our ongoing projects in molecular hematology. **Research focus** You will play a key role in the design and implementation of _in vitro_ culture models using primary human hematopoietic cells, with a particular emphasis on single-cell genomics...
-
Scientific Research Leader Position
4 weken geleden
Utrecht, Utrecht, Nederland Hubrecht Institute VoltijdAbout the Hubrecht InstituteThe Hubrecht Institute is a world-class research institute dedicated to fundamental research in molecular and developmental biology. Located at the Utrecht Science Park in the Netherlands, our institute has a diverse team of 20 group leaders who excel in tackling questions on life's fundamental processes using transformative...
-
Technical Officer
4 weken geleden
Utrecht, Utrecht, Nederland HKU VoltijdHKU Seeks a Highly Skilled Molecular Biology SpecialistThe Department of Obstetrics and Gynaecology at the School of Clinical Medicine, HKU is looking for an exceptional candidate to fill the position of Senior Technical Officer in our prenatal diagnostic laboratory. This is a full-time appointment for one year with a possibility of renewal subject to...
-
Molecular Biologist Intern
1 maand geleden
Utrecht, Utrecht, Nederland Genmab VoltijdInternship OpportunityWe're committed to building extraordinary futures together, by developing antibody products and pioneering therapies that change lives of patients and the future of cancer treatment and serious diseases.Position OverviewOur Cell and Molecular Sciences team is seeking an intern to assist in the design and execution of experiments using...
-
Phd Position On Microbiome-driven Crop Nutrition
2 weken geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdWith the pressing need to reduce the use of synthetic fertilizers, this PhD project explores the microbial interplay between sulfur and nitrogen metabolism in crops like soybean. By utilising advanced metagenomics, transcriptomics, and elemental analysis, the project aims to identify plant-microbe regulatory networks that enhance crop nutrition and...
-
Phd Position in Developmental Biology
6 maanden geleden
Utrecht, Nederland Universiteit Utrecht Voltijd**Your job**: Cell polarity - the asymmetric distribution of components and functions within a cell along a directional axis - is a fundamental property of cells that is present across the kingdoms of life. Most cells need to distribute proteins, organelles, and functions along an axis of polarity in order to carry out their specialised functions and...
-
Technician (Molecular Biology)
3 maanden geleden
Utrecht Oost, Nederland GenDx Voltijd**GenDx, experts in transplant diagnostics** GenDx is a global leader in molecular diagnostic laboratory solutions for high resolution tissue typing of both donors and patients and monitoring transplant success. We combine our cutting-edge software solutions, reagents for DNA sequencing-based HLA typing and Chimerism monitoring strategies with our excellent...
-
Phd Position in Erc Research Project Respire
7 dagen geleden
Utrecht Binnenstad, Nederland Universiteit Utrecht VoltijdPhD position within ERC-funded project RESPIRE to study intersectional power dynamics and socio-environmental in/justice through planetary breathing and suffocation. **Your job**: The PhD position is a part of a research project RESPIRE: Planetary Breathing in Asphyxiating Times lead by Dr. Magdalena Górska and funded by the European Research Council. Your...
-
Phd Position in Philosophy of Science
6 maanden geleden
Utrecht, Nederland Universiteit Utrecht VoltijdScience communication often involves hyped, overly broad claims about research findings. What are the causes, social epistemological risks, and who’s responsible? In this PhD project, you will be researching these questions. **Your job**: We are offering a fully funded four-year PhD position to a researcher interested in philosophically and experimentally...
-
Phd Student
3 maanden geleden
Utrecht, Nederland Koninklijke Nederlandse Akademie van Wetenschappen Voltijd**Location**:Utrecht **Max hours per week**:38.00 **Max salary**:3.670 **Duration of agreement**:15 months (extend after evaluation) **A fully-funded PhD position is immediately available in the new research group led by Miguel Leung, which opens at the Hubrecht Institute in October 2024.** **What you will be doing** The Leung group uses cellular...
-
Intern, Cell
1 maand geleden
Utrecht, Nederland Genmab VoltijdAt Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...
-
2 Phd Positions in Literary and Cultural Studies:
6 maanden geleden
Utrecht, Nederland Universiteit Utrecht Voltijd**Your job**: **Position 1: Poetics of Eco-violence**: This subproject will contribute to recent scholarship on eco-poetics by exploring the aesthetic, political, and affective affordances of literature, specifically poetry, for representing eco-violence, past and ongoing. Special attention will be paid to how contemporary poets are reimagining genres and...
-
Phd Positions: Mechano-catalytic Depolymerisation
3 maanden geleden
Utrecht Oost, Nederland Universiteit Utrecht VoltijdAre you looking to do a PhD project and are you interested in catalysis, spectroscopy, mechano-chemistry, or polymer science to develop a sustainable pathway for plastic waste recycling through mechano-catalytic conversion? Join us in shaping a greener future! **Your job**: The core objective of this project is to pioneer the conversion of polyolefins into...
-
Phd Position improvising Security: Subsistence in
3 maanden geleden
Utrecht Binnenstad, Nederland Universiteit Utrecht Voltijd**Your job**: We are hiring a PhD researcher to participate in the NWO/Vidi project **"I**mprovising Security: Subsistence in Contemporary Urban Europe**"** and to write a dissertation based on urban ethnographic research in Rotterdam, the Netherlands. Urban dwellers in Western Europe are facing new insecurities related to work, care, and access to basic...
-
Phd Candidate Develop Innovative Rna Therapies for
6 maanden geleden
Utrecht, Nederland UMC Utrecht VoltijdJoin our team to develop innovative RNA therapies for monogenic epilepsies and collaborate on cutting-edge research at UMC Utrecht. Collaborate within UMC Utrecht's Genetics Department, contributing to cutting-edge clinical and scientific research.**Elke dag de zorg en de gezondheid van mensen verbeteren**Goede arbeidsvoorwaarden**Jezelf continu blijven...