Postdoc - Advanced Process Control
1 dag geleden
Post Doc - Advanced Process Control
Location: Leiden, Netherlands
Start Date: ASAP
We are looking for a motivated and driven Postdoctoral Scientist to join our team in an innovative automated process control project within cell culture manufacturing. In this role, you will play a key part in developing and implementing sophisticated automation strategies for biologics drug substance production, with a strong emphasis on modeling and process control. You will collaborate closely with the Leiden site and the Global Process Science Modeling & Data teams to demonstrate the potential of model-based feedback control in revolutionizing cell culture processes.
Join us in shaping the future of biologics manufacturing and advancing the next generation of cell culture technologies
Key Responsibilities:
- Design mechanistic models to accurately capture the behavior of various cell lines in cell culture processes
- Infer key model parameters’ values from data
- Design a model-based feedback control loop to dynamically optimize critical process parameters in real-time under hard and soft constraints
- Partner with industry and academia to validate the developed models and control strategy
- Work multi-functionally with internal teams to efficiently implement the designed control strategy
- Present findings and innovations at internal meetings and external scientific conferences
**Qualifications**:
- A strong background in mechanistic modeling and optimization techniques
- A strong background in model-based process control and state estimation techniques
- Proficiency in scientific programming with Python and familiarity with Process Analytical Technology (PAT) tools and sensors
- Familiarity with Bayesian modeling is a plus
- Previous exposure to cell culture manufacturing in a pharmaceutical setting is a plus
- Outstanding ability to identify, analyze, and proactively and independently address potential challenges
- Excellent communication and teamwork skills and ability to work optimally within multi-functional teams
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
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