Biophysics Research Scientist: Unveiling the Ubiquitin Motor Cdc48/p97

2 dagen geleden


Amsterdam, Noord-Holland, Nederland AMOLF Voltijd

The dynamic ubiquitin processing motor Cdc48/p97 plays a pivotal role in cellular functions such as protein degradation, membrane remodeling, and DNA replication regulation. In this project, you will employ innovative (bio)physics experiments to elucidate the mechanism of Cdc48/p97 using optical tweezers and single-molecule fluorescence techniques.

Key Responsibilities

  • Design and conduct novel biophysical experiments to study the action of ubiquitin-processing enzymes
  • Analyze complex temporal data and formulate new models to explain findings
  • Collaborate with international partners in Germany for complementary in-vitro data
  • Develop new experimental schemes and adapt existing biochemical protocols

Qualifications

  • Master's degree or higher in physics, chemistry, or a related field
  • Strong background in single-molecule techniques and biophysics
  • Excellent programming skills for data analysis
  • Ability to work independently and collaboratively in a diverse team environment

Benefits

  • Competitive salary: €2,781 per month gross
  • Full-time appointment for four years
  • Opportunities for professional development and conference attendance
  • Assistance with housing and visa applications for international candidates

About AMOLF

AMOLF is a leading research institute in fundamental research on the physics of complex forms of matter. Our mission is to create new functional materials and develop groundbreaking technologies through interdisciplinary collaboration.



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