PhD Candidate in Molecular Neuroscience

3 weken geleden


Amsterdam, Noord-Holland, Nederland VU Amsterdam Voltijd

Project Overview

Project Description:

Synaptic plasticity, the ability to modify synaptic strength in response to neuronal activity, plays a crucial role in the brain's capacity to encode memories. Our research aims to understand the molecular events that induce long-term alterations in synaptic structure and function. Recent studies have revealed an exciting new level of nano-structural plasticity relevant for memory formation, but the molecular processes coordinating these events remain unresolved. In this project, you will investigate how nanoscale molecular processes at synapses control memory formation using CRISPR/Cas9-based tools, super-resolution microscopy, optogenetics, and electrophysiology.

Your Responsibilities

  • Investigate the molecular processes controlling synapse nanostructure and function using various techniques.
  • Perform and analyze microscopy and electrophysiology data.
  • Publish research findings in peer-reviewed journals and provide progress reports to funding sources.
  • Contribute to teaching activities, including supervision of BSc and/or MSc students during internships.
  • Present research to the international research community.

Requirements

  • A Master's degree in life sciences, biomedical sciences, or biophysics with neuroscience specialization.
  • Hands-on experience with molecular and cellular neuroscience, preferably with molecular biology, (live-cell) fluorescence microscopy, and/or electrophysiology.
  • Experience with imaging and/or bioinformatics is an advantage.
  • Fluency in English (written and spoken) and good communication skills.

What We Offer

  • A challenging position in a socially engaged organization.
  • A salary of € 2,000 (PhD) and maximum € 3,000 (PhD) gross per month in the fourth year, for a full-time employment.
  • An employment contract of initially 1 year, extendable to 4 years with a dissertation at the end of the fourth year.


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