Postdoctoral Research Fellow in Nanomedicine and Drug Delivery

2 weken geleden

Utrecht, Utrecht, Nederland HKU Voltijd

Postdoctoral Research Fellow in Nanomedicine and Drug Delivery

The Department of Pharmacology and Pharmacy at the LKS Faculty of Medicine, HKU, invites applications for a Postdoctoral Research Fellow in Nanomedicine and Drug Delivery. We are seeking a highly motivated and experienced researcher to join our team and contribute to our research projects in the area of nanomedicine and drug delivery.

The successful candidate will have a PhD in a relevant field, such as pharmaceutical sciences, pharmacology, biology, or chemistry. They will have a strong background in research, with experience in designing and developing small molecules, nucleic acids, and peptide therapeutics. They will also have hands-on experience in advanced cell culture techniques and in vivo models.

The research projects in our lab focus on using nanotechnology to better understand, diagnose, and treat diseases, with particular interests in cancer and neurodegenerative diseases. We are a highly collaborative and multidisciplinary lab, and the successful candidate will have the opportunity to work with a team of researchers and clinicians to develop innovative solutions for these diseases.

The successful candidate will be responsible for designing and developing new research projects, conducting experiments, and analyzing data. They will also be responsible for writing reports and scientific articles based on their research results. They will have the opportunity to present their research at international conferences and publish their results in top-tier journals.

The appointment will be for 1 year, with the possibility of renewal up to 3 years, subject to satisfactory performance and funding availability. A highly competitive salary commensurate with qualifications and experience will be offered. Other benefits include annual leave, medical benefits, and free access to on-campus gyms and libraries.

Responsibilities:

  • Design and develop small molecules, nucleic acids, and peptide therapeutics.
  • Design, prepare, and characterize nanoparticles.
  • Employ state-of-the-art techniques to assess the physicochemical properties of nanoparticles.
  • Conduct cell culture studies using cell lines, primary cultures, and/or patients' tissues for efficacy evaluation.
  • Conduct in vivo studies, including administration of nanoparticles, monitoring fate, therapeutic response, and assessing the impact on disease progression.
  • Develop relevant disease models to assess therapeutic efficacy of a specific treatment.
  • Demonstrate understanding of the disease pathology for better design of advanced therapeutics.
  • Coordinate with clinical collaborators to obtain ethical approvals and obtaining human tissue samples for subsequent studies.
  • Engage in collaborative projects both internally and externally.
  • Periodically report progress to PI, co-investigators, project collaborators, and project funder.
  • Initiate and contribute to grant writing activities.
  • Write study-specific procedures for analytical methods, protocols, and reports and provide training on processes and equipment.
  • Supervise and co-supervise undergraduate and postgraduate students.
  • Disseminate research findings through the preparation of research articles and presentations at international conferences.
  • Foster an agile and friendly working environment within the research group.

Requirements:

  • PhD in Pharmaceutical Sciences, Pharmacology, Biology, Molecular Biology, Biochemistry, Immunology, Bioengineering, Chemistry, Data Science, or related fields.
  • Postdoctoral experience preferred.
  • Proven track record in conducting high-quality biological or chemical research.
  • Demonstrated history of writing reports and scientific articles based on research results.

Desirable Skills:

  • Hands-on experience in advanced cell culture techniques and in vivo models.
  • Proficiency in various cell and molecular biology experimentation techniques like PCR, gels, Western blotting, Immunohistochemistry, ELISA, and flow cytometry, immune profiling.
  • Experience in bioconjugations.

Administrative and Collaborative Skills:

  • Ability to manage a research programme financially and administratively under the guidance of the Principal Investigator.
  • Ability to work independently with excellent problem-solving skills, collaborate within a team, and supervise students.
  • High attention to detail in experimental design and execution with a willingness to adapt to new procedures and undergo further training as necessary.

Language and Technical Competence:

  • Excellent command of written and spoken English.
  • Capable of writing grants and contributing to additional funding acquisition.
  • Proficient in IT skills for efficient data management and communication within the research programme.

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