Assistant Professor in Computer-Aided Drug Design

2 dagen geleden


Amsterdam, Noord-Holland, Nederland Vrije Universiteit Amsterdam Voltijd
About the Position

We are seeking an Assistant Professor to lead the Computer-Aided Drug Design (CADD) group within the Medicinal Chemistry division at Vrije Universiteit Amsterdam. The successful candidate will develop methodologies in molecular modeling, data management, and machine learning to advance the understanding of ligand-protein interactions.

The candidate will have a background in drug development, medicinal chemistry, and computational chemistry, with expertise in both ligand-based and structure-based drug discovery. The role requires interdisciplinary collaboration within the division, working closely with synthetic chemists and molecular pharmacologists.

Key Responsibilities
  • Develop and apply computational techniques, including protein structure predictions, molecular dynamics, docking, virtual screening, structural chemogenomics, machine learning, and free-energy perturbations.
  • Manage and analyze large datasets, with expertise in cheminformatics and bioinformatics.
  • Model G-protein coupled receptors and enzymes, with a strong publication record.
  • Program and script, with good communicative skills in writing and speaking.
  • Attract research funding and lead the CADD group.
  • Motivate and teach graduate and undergraduate students.
About the Department

The Medicinal Chemistry division is part of the Faculty of Science at Vrije Universiteit Amsterdam. The department has two main research lines: G protein-coupled receptors (GPCRs) and Fragment-Based Drug Discovery. The computational group uses structural understanding to develop GPCR activation models, construct ligand-protein binding models, deduce structure-activity relationships, and identify and optimize novel GPCR ligands.

The department is committed to research, valorisation, and training socially engaged citizens of the world who will make valuable contributions to a sustainable, healthy future.

About the University

Vrije Universiteit Amsterdam stands for values-driven education and research. We are open-minded experts with the ability to think freely. We work on sustainable solutions with social impact, concentrating on diversity, significance, and humanity. We strive for an inclusive community and believe that diversity and internationalisation contribute to the quality of education, research, and our services.

We are located on one physical campus, in the heart of Amsterdam's Zuidas business district, with excellent location and accessibility. Over 6,150 staff work at the VU, and over 31,000 students attend academic education.



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    About the PositionWe are seeking an exceptional candidate to join our team as an Assistant Professor in Computer-Aided Drug Design at VU Amsterdam. As a key member of our Medicinal Chemistry division, you will lead the Computer-Aided Drug Design group and contribute to the development of innovative methodologies in molecular modeling, data management, and...


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