Huidige banen gerelateerd aan Postdoc Position in Yeast Molecular Biology - Utrecht - Universiteit Utrecht
-
Molecular Biologist Intern
6 dagen geleden
Utrecht, Utrecht, Nederland Genmab VoltijdInternship OpportunityWe're committed to building extraordinary futures together, by developing antibody products and pioneering therapies that change lives of patients and the future of cancer treatment and serious diseases.Position OverviewOur Cell and Molecular Sciences team is seeking an intern to assist in the design and execution of experiments using...
-
Senior Technical Officer
5 dagen geleden
Utrecht, Utrecht, Nederland HKU VoltijdMolecular Biology ExpertThe appointee will work in a prenatal diagnostic laboratory, performing laboratory work and analysis on molecular genetics, and assisting in research and development of new molecular techniques.Applicants should have a Master's degree or equivalent in Molecular Biology or related disciplines, with at least 2 years' hands-on laboratory...
-
Intern, Cell
1 week geleden
Utrecht, Nederland Genmab VoltijdAt Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...
-
Phd Position in Molecular Control of
5 maanden geleden
Utrecht, Nederland Universiteit Utrecht VoltijdThe immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate how plants control their growth during and after an immune response. This research...
-
Phd Position: Molecular Mechanisms of Protein
5 maanden geleden
Utrecht, Nederland Universiteit Utrecht Voltijd**Your job**: We are working at the interface of biochemistry, molecular biology and biophysics to follow the journey of nascent proteins toward their functional structures as they emerge from the ribosome. These mechanistic studies pave the way for targeted interventions against protein misfolding and perturbed protein homeostasis which are important for a...
-
Senior Technical Officer
3 weken geleden
Utrecht, Utrecht, Nederland HKU VoltijdSenior Technical Officer in the Department of Obstetrics and Gynaecology, School of Clinical MedicineApplicants should have a Master's degree or equivalent in Molecular Biology or related disciplines, with at least 2 years' hands-on laboratory experience in molecular biology and medical genetics. Registration with the Hong Kong Medical Laboratory...
-
Senior Technical Officer
2 weken geleden
Utrecht, Utrecht, Nederland HKU VoltijdSenior Technical Officer in the Department of Obstetrics and Gynaecology, School of Clinical MedicineApplicants should have a Master's degree or equivalent in Molecular Biology or related disciplines, with at least 2 years' hands-on laboratory experience in molecular biology and medical genetics. Registration with the Hong Kong Medical Laboratory...
-
Senior Technical Officer
2 weken geleden
Utrecht, Utrecht, Nederland HKU VoltijdJob Title: Senior Technical OfficerJob Summary:We are seeking a highly skilled Senior Technical Officer to join our team at the Department of Obstetrics and Gynaecology, School of Clinical Medicine. The successful candidate will be responsible for performing laboratory work and analysis on molecular genetics, and assisting in research and development of new...
-
Technical Officer for Molecular Biology Research
6 dagen geleden
Utrecht, Utrecht, Nederland HKU Voltijd{'Job Title': "Senior Technical Officer", 'Job Description': "Technical ExpertiseThe appointee will perform laboratory work and analysis on molecular genetics, utilizing expertise in molecular biology and medical genetics. Proficiency in setting up PCR and DNA Sanger sequencing reactions is required.Key ResponsibilitiesAssist in research and development of...
-
Phd Position in Molecular Control of
5 maanden geleden
Utrecht, Nederland Universiteit Utrecht VoltijdThe immune system helps plants resist pathogen infections and has been well studied. However, it becomes increasingly clear that enhancing defense comes at a cost, as plants slow down growth even if the infection is successfully combatted. In this project, you will investigate the poorly understood process of how plants control their growth during and after...
-
Technician (Molecular Biology)
1 maand geleden
Utrecht Oost, Nederland GenDx Voltijd**GenDx, experts in transplant diagnostics** GenDx is a global leader in molecular diagnostic laboratory solutions for high resolution tissue typing of both donors and patients and monitoring transplant success. We combine our cutting-edge software solutions, reagents for DNA sequencing-based HLA typing and Chimerism monitoring strategies with our excellent...
-
Phd Position in Developmental Biology
5 maanden geleden
Utrecht, Nederland Universiteit Utrecht Voltijd**Your job**: Cell polarity - the asymmetric distribution of components and functions within a cell along a directional axis - is a fundamental property of cells that is present across the kingdoms of life. Most cells need to distribute proteins, organelles, and functions along an axis of polarity in order to carry out their specialised functions and...
-
Molecular Biology Specialist
2 maanden geleden
Utrecht, Utrecht, Nederland HKU VoltijdJob SummaryThe University of Hong Kong is seeking a highly motivated and experienced Postdoctoral Fellow to join the Division of Cardiology. The successful candidate will contribute to ongoing research projects on gene-editing and other strategies for developing new therapeutic approaches against cardiovascular disorders and other inherited diseases.Key...
-
Postdoctoral Researcher in Molecular Hematology
5 maanden geleden
Utrecht, Nederland Prinses Máxima Centrum VoltijdWe are seeking a highly motivated and talented Postdoctoral Researcher to join our team and contribute to our ongoing projects in molecular hematology. **Research focus** You will play a key role in the design and implementation of _in vitro_ culture models using primary human hematopoietic cells, with a particular emphasis on single-cell genomics...
-
Senior Technical Officer
1 week geleden
Utrecht, Utrecht, Nederland HKU VoltijdJob DescriptionThe appointee will perform laboratory work and analysis on molecular genetics in a prenatal diagnostic laboratory.RequirementsApplicants should have a Master's degree or equivalent in Molecular Biology or related disciplines, with at least 2 years' hands-on laboratory experience in molecular biology and medical genetics.Registration with the...
-
Postdoctoral Researcher
6 dagen geleden
Utrecht, Utrecht, Nederland Koninklijke Nederlandse Akademie van Wetenschappen VoltijdJob DescriptionWe are seeking a highly motivated Postdoc to join our research team at the Hubrecht Institute. The successful candidate will work closely with our international team to investigate the mechanisms and effects of Human Milk Oligosaccharides (HMOs) on the immune system and intestinal epithelium.Key ResponsibilitiesDesign and conduct experiments...
-
Postdoc - Therapeutic Gene Delivery
1 maand geleden
Utrecht, Nederland UMC Utrecht Voltijd**Elke dag de zorg en de gezondheid van mensen verbeteren**Goede arbeidsvoorwaarden**Jezelf continu blijven ontwikkelen vinden we belangrijk** **Dit ga je doen** **Hier ga je werken** The position is embedded within the Department of Translational Neuroscience of UMC Utrecht. The project focusses on building an in-house viral vector production platform...
-
Principal Investigator Position at the Hubrecht Institute
1 week geleden
Utrecht, Utrecht, Nederland Hubrecht Institute VoltijdTenure-Track Principal Investigator PositionThe Hubrecht Institute invites applications for a tenure-track group leader position. We are interested in candidates with curiosity-driven, innovative research plans in the domain of molecular and developmental biology that can synergize with ongoing research in the institute. We welcome applications from...
-
Research Associate, High Throughput Molecular Tools
5 maanden geleden
Utrecht, Nederland Genmab VoltijdAt Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in...
-
Utrecht, Utrecht, Nederland Universiteit Utrecht VoltijdJob DescriptionWe are seeking a highly motivated postdoctoral researcher to join our team at the Institute for Risk Assessment Sciences (IRAS) as part of the NCOH-ZonMW Pandemic Preparedness Kickstart Program.ResponsibilitiesDevelop and further refine eDNA barcoding methods for host species detection and quantification in air samples.Quantify host-derived...
Postdoc Position in Yeast Molecular Biology
4 maanden geleden
Ready for creative research to tackle key questions on biological membranes? Join us as a Postdoc and dive into groundbreaking scientific exploration.
Ready for creative research to tackle key questions on biological membranes? Want to join us as a Post-doc and dive into groundbreaking scientific exploration? Apply now
Your jobIn this NWO-funded project, you will investigate the regulation of acetyl-CoA carboxylase (Acc1) and fatty acid synthase (FAS) in establishing the average acyl chain length of membrane lipids in yeast.
Proper function of membranes and membrane proteins critically depends on the regulation of the fluidity (viscosity) of the membrane’s lipid matrix. In response to e.g. a change of the ambient temperature, the model eukaryote S. cerevisiae adjusts the fluidity of its membranes by tuning the level of unsaturation and the average length of the membrane lipid acyl chains. Whereas the mechanism of the former has been solved, the regulation of acyl chain length remains a mystery, although this more subtle mechanism may be equally important for membrane function. Your project will address this challenging fundamental question at the interface of yeast genetics, cell biology, and membrane biochemistry and biophysics.
You will investigate the regulation of acetyl-CoA carboxylase (Acc1) and fatty acid synthase (FAS) in establishing the average acyl chain length of membrane lipids in yeast. In fatty acid synthesis, Acc1 synthesises malonyl-CoA that is iteratively consumed by FAS in producing C16 or C18 fatty acyl-CoA. Based on data obtained by us and others, we hypothesise that the C16/C18 ratio of the acyl-CoA produced is determined by the relative activities of these 2 key enzymes, i.e. increased activity of Acc1 vs. FAS favors a rise in C18 over C16 and vice versa.
You will investigate how yeast regulates Acc1 vs. FAS activity by designing and engineering a set of mutants, and applying a range of biochemical, genetic, -omics, and (fluorescence) microscopy approaches to uncover the underlying mechanisms.
Your tasks and responsibilities will include:
- conducting independent research in the regulation of yeast membrane lipid composition, resulting in academic publications in peer-reviewed international journals;
- supervising Bachelor's and Master's thesis projects with topics relevant to your project;
We are looking for an ambitious and creative molecular life scientist who is interested in working at the interface of biochemistry, genetics and biophysics. You enjoy being part of an interdisciplinary team of scientists, and meet multiple of the following criteria:
- You have a PhD in molecular biology, genetics, biotechnology or related discipline.
- You have demonstrated experience with (yeast) molecular biology and genetics.
- You have a strong interest in (yeast) membrane and cell biology.
- You are strongly motivated, flexible, and able to run multiple projects simultaneously.
- You have a professional command of English, both in writing and speaking.
We offer:
- a position for one year, which will be extended to three and a half years after positive evaluation.
- a working week of 38 hours and a gross monthly salary – depending on previous qualifications and experience – between €3,226 and €5,090 in the case of full-time employment (salary scale 10 under the Collective Labour Agreement for Dutch Universities (CAO NU));
- 8% holiday pay and 8.3% year-end bonus;
- a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.
In addition to the terms of employment laid down in the CAO NU, Utrecht University has a number of schemes and facilities of its own for employees. This includes schemes facilitating professional development, leave schemes and schemes for sports and cultural activities, as well as discounts on software and other IT products. We also offer access to additional employee benefits through our Terms of Employment Options Model. In this way, we encourage our employees to continue to invest in their growth. For more information, please visit Working at Utrecht University.
About usA better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. Sharing science, shaping tomorrow.
Working at the Faculty of Science means bringing together inspiring people across disciplines and with a variety of perspectives and backgrounds. The Faculty has six departments: Biology, Pharmaceutical Sciences, Information & Computing Sciences, Physics, Chemistry and Mathematics. Together, we work on excellent research and inspiring education. We do so, driven by curiosity and supported by outstanding infrastructure. Visit us on LinkedIn and discover how you can become part of our community.
Research in the Membrane Biochemistry and Biophysics group focusses on the molecular mechanisms of cellular processes that involve biological membranes. We aim to unravel mechanisms underlying membrane assembly, homeostasis and function, with special emphasis on the lipid-protein interactions involved. Our research will help improve fundamental understanding of membrane function and provide insights in membrane-related diseases (such as diabetes, Alzheimer’s disease). In flanking applied research we investigate the modes of action of e.g. membrane-active drugs. Within MBB the team of Toon de Kroon studies membrane lipid homeostasis in the reference eukaryote S. cerevisiae. MBB participates in the Bijvoet Centre for Biomolecular Research and in the Institute of Biomembranes.
More informationFor more information, please contact Dr. Toon de Kroon via a.i.p.m.dekroon@uu.nl.
Do you have a question about the application procedure? Please send an email to science.recruitment@uu.nl.
Apply nowAs Utrecht University, we want to be a home for everyone. We value staff with diverse backgrounds, perspectives and identities, including cultural, religious or ethnic background, gender, sexual orientation, disability or age. We strive to create a safe and inclusive environment in which everyone can flourish and contribute.
If you are enthusiastic about this position, just apply via the "Apply now" button Please enclose:
- your letter of motivation;
- your curriculum vitae;
- The names, telephone numbers, and email addresses of at least two references;
- Optional: a copy of your PhD certificate, or a letter from your university stating when your defence will take place.
If this specific opportunity isn’t for you, but you know someone else who may be interested, please forward this vacancy to them.
