Research Associate, Shared Neoantigen Tcr Discovery
1 maand geleden
At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.
**Position Summary**
Neogene is looking for you to join our shared neoantigen T cell receptor (TCR) discovery research team as a **Research Associate**. You will assume responsibilities for conducting experimental and pre-clinical work aiming to develop shared neoantigen-based T cell therapies. The position is based in Amsterdam, The Netherlands, and you will report to the Shared neoantigen TCR discovery team lead.
**Responsibilities**
- Perform TCR isolation and characterization studies under the supervision of senior research staff. Involved techniques include density gradient-, magnetic bead
- and flow cytometry-based isolation of human immune cells (T cells, B cells, Dendritic cells and others), phenotypic and functional evaluation of immune cells by flow cytometry (surface and intracellular staining, proliferation tracking, cytotoxicity assays) and genetic modification of primary immune cells and cell lines using retro-/lenti-viruses and gene editing tools (e.g. CRISPR-Cas9).
- Support assay development
- Document experimental results in electronic laboratory journal and databases.
- Presenting obtained results in internal work-discussions.
- Complete tasks relating to laboratory operations under guidance of the Lab-manager.
- Other responsibilities and special projects as assigned.
**Education and Experience**
- Bachelor or Master's in Biomedical Sciences or a related field, recently graduated you are invited to apply.
- Industry experience is a plus.
- Knowledge on aseptic cell culture techniques and first-hand experience with multi-color flow cytometry is required.
- Additional training in the area of B and T cell culture, genetic manipulation of cells using retroviruses, lentiviruses or gene editing tools (e.g. CRISPR-Cas9), molecular biology (next-generation sequencing and vector design/construction) in a plus.
- Excellent organizational skills, a strong sense of urgency and responsibility with regards to work duties and the ability to deliver results based on challenging timelines.
- Strong verbal and written communication skills in English.
- Comfortable in a fast-paced growing company environment and able to adjust workload based upon changing priorities.
- We are looking for a person who will lead by example and is a self-motivated team player with strong interpersonal skills.
- Authorization to work with GMOs is preferred.
- You must be authorized to work in The Netherlands.
LI-Onsite
**DE&I Statement
-
Senior Immunologist, Neoantigen TCR Discovery Team
7 dagen geleden
Amsterdam, Noord-Holland, Nederland Neogene Therapeutics VoltijdAre you passionate about harnessing the power of immunology to drive innovation in cancer treatment?We are seeking a highly motivated and experienced Senior Immunologist to join our Neoantigen TCR Discovery Team at Neogene Therapeutics. As a key member of our team, you will be responsible for conducting cutting-edge research to develop novel shared...
-
Research Scientist, Immune Cell Therapies
4 weken geleden
Amsterdam, Noord-Holland, Nederland Neogene Therapeutics VoltijdAstra Zeneca's Oncology R&D division is at the forefront of exploring and innovating in the field of cancer treatment. As a Research Associate on our Shared Neoantigen TCR Discovery Team, you will play a crucial role in conducting experimental and pre-clinical work to develop shared neoantigen-based T cell therapies.The position is based in Amsterdam, The...
-
Research Associate R&d, Molecular Biology and
4 maanden geleden
Amsterdam, Nederland Neogene Therapeutics VoltijdAt AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a...
-
Research Associate, Tcr Selection Facility
6 maanden geleden
Amsterdam, Nederland Neogene Therapeutics VoltijdPushing the frontier of solid cancer therapy, Neogene Therapeutics is a global, clinical stage biotechnology company built on the premise of innovation and novel paradigm-changing science. Using tumor mutation profiles to engineer fully individualized T cell therapies, Neogene is bringing new hope to address the current limitations of treatments available...
-
(Associate) Director
7 maanden geleden
Amsterdam, Nederland CureVac Voltijd**(Associate) Director (f/m/d) Cancer Antigen Discovery** **Your Responsibilities**: - Lead a team of cancer genomics and computational scientists (~8 FTEs) - Participate in global project teams to represent the cancer antigen discovery team - Identify and initiate possibilities to collaborate with academic and industrial partners to accelerate the...
-
Mellon Research Associate
4 weken geleden
Amsterdam, Noord-Holland, Nederland Rijksmuseum VoltijdResearch Opportunities at the RijksmuseumWe are seeking highly talented candidates to participate in our Fellowship Programme, which aims to encourage and support scholarly investigation in the field of art and cultural history.Focus AreasThe programme focuses on the Netherlands as an international intersection of art, artists, artistic ideas and...
-
Biopharmaceutical Clinical Research Associate Specialist
4 weken geleden
Amsterdam, Noord-Holland, Nederland Allucent VoltijdJoin Our Team as a Biopharmaceutical Clinical Research Associate SpecialistWe are seeking a highly skilled Biopharmaceutical Clinical Research Associate Specialist to join our team at Allucent, a leading provider of clinical trial solutions. As a CRA Specialist, you will play a critical role in ensuring the success of our clients' clinical trials.About...
-
Clinical Research Associate Lead
4 weken geleden
Amsterdam, Noord-Holland, Nederland Allucent VoltijdAbout AllucentWe are a dedicated team at Allucent, helping small-medium biopharmaceutical companies navigate the complex world of clinical trials to bring life-changing therapies to patients globally.Our goal is to provide top-notch services that ensure the success of our clients' projects.Job SummaryWe are seeking an experienced Clinical Research Associate...
-
Regulatory Operations Associate, Index Governance
2 maanden geleden
Amsterdam, Nederland S&P Global, Inc. VoltijdRegulatory Operations Associate, Index Governance (S&P Dow Jones Indices) **About the Role**: **Grade Level (for internal use)**: 11 **About the Role**: **The Team**: The Regulatory Operations Associate will be a member of the Index Governance Operations team at S&P Dow Jones Indices. The team is committed to ensuring that S&P DJI's indices are operated in...
-
Phd Position intercultural Triadic Shared
3 weken geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdPhD Position "Intercultural Triadic Shared Decision-Making in Mental Healthcare" **Faculty/Services**:Faculty of Social and Behavioural Sciences**Educational level**:Master**Function type**:PhD position**Closing date**:3 January 2025**Vacancy number**:13662- - PhD Opportunity: Enhancing Triadic Shared Decision-Making for Migrants- - Shared decision-making...
-
Associate Market Research Director
2 maanden geleden
Amsterdam, Nederland MMR Research Worldwide LTD VoltijdAre you an experienced researcher with a commercial mindset and a proven ability to grow accounts? Are you curious and passionate about client first? Are you a fast learner that values your client’s business first and fore-most? If so, MMR may have the role for you!We are looking for a highly motivated individual who is strong in research and account...
-
Associate Director
6 maanden geleden
Amsterdam, Nederland UNStudio VoltijdAssociate Director Exciting opening at UNStudio! Become a leader for one of our teams, reporting to the Director. Full-time - Amsterdam As an Associate Director, also called Associate Design Director, you will be in a multi-dimensional role. In a nutshell, you will be leading the design development, mentoring senior architects and curating the process at...
-
Research Analyst, Agricultural Sustainability
2 maanden geleden
Amsterdam Centrum, Nederland S&P Global Voltijd**About the Role**: **Grade Level (for internal use)**: 09 **The Team**: We are looking for an agricultural specialist to join S&P Global Commodity Insights’ dynamic Agribusiness Research, to help drive Agribusiness Sustainability data and research. The Agribusiness group offers data and research solutions on major crops and food commodities, fertilizers,...
-
Vp, Head of Research and Vector Development
4 maanden geleden
Amsterdam, Nederland uniQure Voltijd**VP, Head of Research and Vector Development** **Location**: - Amsterdam (Netherlands)**Education level**: - PhD**Job category**: - Research**Target start date**: - 1/6/2025**Work Location**: - On-Site**Shift**: - 1stThe Research and Vector Development team is responsible for driving the early stage pipeline in line with the corporate objectives....
-
Senior Bioinformatics Researcher Computational Cancer Genomics
4 weken geleden
Amsterdam, Noord-Holland, Nederland CureVac VoltijdWe are seeking an experienced Senior Bioinformatics Researcher to join our Oncology Antigen Discovery and Computational Research team in Amsterdam, the Netherlands. This is a unique opportunity to contribute to the analysis of proteomics, genomics, and transcriptomics data from internal and external sources with the aim to identify and select personalized as...
-
Real Estate Associate
4 maanden geleden
Amsterdam, Nederland Bruin VoltijdB- Posted by - Bianca Romao-Willis- RecruiterOur client is a global name within real estate investments. Due to continued growth in the Netherlands, they are now seeking an Associate - Real Estate (Logistics) to join their dynamic team in Amsterdam. Key responsibilities of the Associate - Real Estate (Logistics): - Support the portfolio manager in managing...
-
Associate, Amsterdam
4 weken geleden
Amsterdam, Nederland Human Rights Watch Voltijd**FIXED-TERM, FULL-TIME JOB VACANCY** **ASSOCIATE** **Development and Outreach Department** **Amsterdam Office** **Application Deadline: 9 December 2024** The Development and Outreach Department of Human Rights Watch (HRW) is seeking a full-time Associate in its Amsterdam office, which serves as an important base for HRW's development, fundraising, and...
-
Clinical Research Associate
7 maanden geleden
Amsterdam, Nederland Novartis Voltijd**Summary**: Monitort patiëntgegevens & studiegerelateerde informatie met betrekking tot klinische onderzoekslocaties en deelname aan klinische proeven.. Zorgt ervoor dat de onderzoeker zich houdt aan onderzoeksprotocollen, wettelijke vereisten en goede klinische praktijken en levert input in datavalidatieplan. Biedt tijdige en nauwkeurige monitoring van...
-
Sales Associate
2 weken geleden
Amsterdam-Zuidoost, Nederland TEK Systems VoltijdOverview: **Fast tracking your career to Account Manager** TEKsystems’® unmatched success in the IT Services and Talent Management marketplace is driven by one thing - our employees. A thriving IT industry has caused us to grow at a rapid pace and we are looking for Sales Associates to join our team with a view to fast tracking through a 20-week...
-
Sales Associate
2 maanden geleden
Amsterdam-Zuidoost, Nederland TEK Systems VoltijdOverview: **Fast tracking your career to Account Manager** TEKsystems’® unmatched success in the IT Services and Talent Management marketplace is driven by one thing - our employees. A thriving IT industry has caused us to grow at a rapid pace and we are looking for Sales Associates to join our team with a view to fast tracking through a 20-week...