PhD Position in Gut Microbiome in Early Life
1 maand geleden
What are you going to do
?
You will study the interactions among maternal factors, infant gut microbiota, and intestinal health aimed at understanding the underlying mechanisms. With our unique Gut on a chip physiomimetic GUMI platform and ‘omics’ analytical facilities, you will characterize the metabolic function of infant gut microbes under conditions that are relevant to clinical observations.
Using synthetic microbial communities, organoids, and gut-microbe coculture models, you will investigate the influence of maternal factors on the gut microbiota’s metabolic functions and how these functional changes modulate gut epithelium and immune function in early life, with a particular focus on metabolic function and naïve T cell maturation. You are expected to identify bacterial species, metabolites, or genes that are key in mediating mother-microbiota-infant interactions.
This position is embedded at the Molecular Biology and Microbial Food Safety group at the Swammerdam Institute for Life Sciences, University of Amsterdam. You will be co-supervised by dr. Jianbo Zhang and Prof. dr. Stanley Brul (promotor).
What do we require?
You have/are
• a degree (MSc, or equivalent) in Microbiology, Molecular Biology, Biochemistry, Immunology, Biomedical Sciences,
or closely related fields. Candidates in the final stages of obtaining their degree are eligible to apply;
• hands-on experience in anaerobic culturing, genetic engineering, cell culture, organoids,
or microphysiological systems;
• additional experience with genetic engineering or omics data analysis is an asset;
• strongly motivated, highly curious, problem-solving, a teamplayer who can also work independently;
• fluent in English, both written and spoken.
Our offer
We offer a temporary contract for 38 hours per week for the duration of 4 years (the initial contract will be for a period of 18 months and after satisfactory evaluation it will be extended for a total duration of 4 years). This should lead to a dissertation (PhD thesis). We will draft an educational plan that includes attendance of courses and (international) meetings. We also expect you to assist in teaching undergraduates and master students.
Based on a full-time appointment (38 hours per week) the gross monthly salary will range from € in the first year to € (scale P) in the last year. This is exclusive 8% holiday allowance and 8.3% end-of-year bonus. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.
Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Take a look here.
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