Phd Position in Gut Microbiome in Early Life
2 dagen geleden
PhD Position in Gut Microbiome in Early Life
**Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**:01.06.2024**Vacaturenummer**:12953- Gut microbiota develop rapidly during early life and are essential for our health during infancy and later life. Many factors potentially impact on this development, including but not limited to delivery modes, neonatal feeding (breast or formula), exposure to antibiotics, and both maternal and infant diet. Changing gut microbiota by these factors, in turn, can substantially impact the immune system, hence the infant’s susceptibility to the development of chronic diseases.- However, how these factors regulate our gut microbiota, immune systems, and interactions is mostly mechanistically still unclear. Understanding this complex interaction will pave the way to the discovery of new targets for interventions aimed at improving metabolic health. This position is supported by the NWA program METAHEALTH focussing on oral and metabolic health.**What are you going to do?**
You will study the interactions among maternal factors, infant gut microbiota, and intestinal health aimed at understanding the underlying mechanisms. With our unique Gut on a chip physiomimetic GUMI platform and ‘omics’ analytical facilities, you will characterize the metabolic function of infant gut microbes under conditions that are relevant to clinical observations.- Using synthetic microbial communities, organoids, and gut-microbe coculture models, you will investigate the influence of maternal factors on the gut microbiota’s metabolic functions and how these functional changes modulate gut epithelium and immune function in early life, with a particular focus on metabolic function and naïve T cell maturation. You are expected to identify bacterial species, metabolites, or genes that are key in mediating mother-microbiota-infant interactions.- This position is embedded at the Molecular Biology and Microbial Food Safety group at the Swammerdam Institute for Life Sciences, University of Amsterdam. You will be co-supervised by dr. Jianbo Zhang and Prof. dr. Stanley Brul (promotor).**What do we require?**
You have/are- a degree (MSc, or equivalent) in Microbiology, Molecular Biology, Biochemistry, Immunology, Biomedical Sciences,- hands-on experience in anaerobic culturing, genetic engineering, cell culture, organoids,
- or microphysiological systems;- additional experience with genetic engineering or omics data analysis is an asset;
- strongly motivated, highly curious, problem-solving, a teamplayer who can also work independently;
- fluent in English, both written and spoken.
**Our offer**
We offer a temporary contract for 38 hours per week for the duration of 4 years (the initial contract will be for a period of 18 months and after satisfactory evaluation it will be extended for a total duration of 4 years). This should lead to a dissertation (PhD thesis). We will draft an educational plan that includes attendance of courses and (international) meetings. We also expect you to assist in teaching undergraduates and master students.-
- Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Take a look here.**Questions?**
Do you have questions about this vacancy? Or do you**About us**
- The Faculty of Science has a student body of around 7,000, as well as 1,600 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain.
- The Swammerdam Institute for Life Sciences is one of the Faculty of Science’s largest institutes. Its approximately 240 scientists and staff members work in 19 research groups that perform excellent research centered on four themes: Neurosciences, Cell & Systems Biology, Microbiology and Green Life Sciences.**Application**- Applications in.pdf should include:
- a motivation letter and CV,
- contact information of referees.
- Please mention the months (not just years) in your CV when referring to your education and work experience.-
- A knowledge security check can be part of the selection procedure.
- (for details: National knowledge security guidelines)- The UvA is an equal-opportunity employer. We prioritize diversity and are committed to creating an inclusive environment for everyone. We value a spirit of enquiry and perseverance, provide the space to keep asking questions, and promote a culture of curiosity and creativity._
-
Phd Position in Gut Microbiome in Early Life
1 week geleden
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdPhD Position in Gut Microbiome in Early LifeFaculteit/Dienst:Faculteit der Natuurw, Wiskunde & InformaticaOpleidingsniveau:MasterFunctie type:PromotieplaatsSluitingsdatum: Vacaturenummer:12953- Gut microbiota develop rapidly during early life and are essential for our health during infancy and later life. Many factors potentially impact on this development,...
-
PhD Position in Gut Microbiome in Early Life
1 maand geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? You will study the interactions among maternal factors, infant gut microbiota, and intestinal health aimed at understanding the underlying mechanisms. With our unique Gut on a chip physiomimetic GUMI platform and ‘omics’ analytical facilities, you will characterize the metabolic function of infant gut microbes under...
-
PhD position MetaHealth
3 weken geleden
Amsterdam, Nederland Vrije Universiteit Amsterdam VoltijdPhD Opportunity: Exploring Host-Oral Microbiome Interactions in Early Life Through 3D Organotypic Models Your function This PhD project is supported by the NWA program METAHEALTH, which focuses on oral and metabolic health in the first 1000 days of life. The PhD candidate will collaborate closely with fellow PhD students studying social behaviour,...
-
Phd Position in Computational Metabolic Modelling
2 maanden geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdPhD Position in Computational Metabolic Modelling of the Infant Gut and Oral Microbiome **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**:01.06.2024**Vacaturenummer**:12952- Gut and oral microbiota develop rapidly during early life and are essential for our health...
-
Phd Position in Computational Metabolic Modelling
2 dagen geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdPhD Position in Computational Metabolic Modelling of the Infant Gut and Oral Microbiome **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**:01.06.2024**Vacaturenummer**:12952- Gut and oral microbiota develop rapidly during early life and are essential for our health...
-
PhD position MetaHealth
1 maand geleden
Amsterdam, Nederland Vrije Universiteit Amsterdam VoltijdPhD Opportunity: Exploring Host-Oral Microbiome Interactions in Early Life Through 3D Organotypic ModelsYour functionThis PhD project is supported by the NWA program METAHEALTH, which focuses on oral and metabolic health in the first 1000 days of life. The PhD candidate will collaborate closely with fellow PhD students studying social behaviour, mathematical...
-
PhD position MetaHealth
4 weken geleden
Amsterdam, Nederland Vrije Universiteit Amsterdam VoltijdPhD Opportunity: Exploring Host-Oral Microbiome Interactions in Early Life Through 3D Organotypic ModelsYour functionThis PhD project is supported by the NWA program METAHEALTH, which focuses on oral and metabolic health in the first 1000 days of life. The PhD candidate will collaborate closely with fellow PhD students studying social behaviour, mathematical...
-
Phd Position in Computational Metabolic Modelling
1 week geleden
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdPhD Position in Computational Metabolic Modelling of the Infant Gut and Oral MicrobiomeFaculteit/Dienst:Faculteit der Natuurw, Wiskunde & InformaticaOpleidingsniveau:MasterFunctie type:PromotieplaatsSluitingsdatum: Vacaturenummer:12952- Gut and oral microbiota develop rapidly during early life and are essential for our health during infancy and later in...
-
Amsterdam, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? You are expected: • to complete a PhD thesis within the official appointment duration of four years; • to develop metabolic models of microbiome species and perform simulations in a community setting to study the infant gut and oral microbiome and relate external factors, such as feeding behaviour, to changes ...
-
Phd Position Metahealth
3 weken geleden
Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam Voltijd**Your function**: The aim of this PhD project is to delve into the mechanisms underlying the establishment of a healthy host-oral microbiome balance in early life **Your duties** Your responsibilities are 1. improving the existing 3D reconstructed human gingiva model in order to better mimic the microbial exposure infants encounter in their oral cavity;...
-
Phd Position Metahealth
1 week geleden
Amsterdam Zuid, Nederland Vrije Universiteit Amsterdam VoltijdYour function:The aim of this PhD project is to delve into the mechanisms underlying the establishment of a healthy host-oral microbiome balance in early lifeYour dutiesYour responsibilities are 1. improving the existing 3D reconstructed human gingiva model in order to better mimic the microbial exposure infants encounter in their oral cavity; 2. exploring...
-
Amsterdam, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? Model Development: Collaborate with an interdisciplinary team of researchers to integrate data from cohort studies, metabolomics analyses and in vitro experiments, to develop computational models relying on spatial modelling techniques such as cellular Potts and reaction-diffusion models that capture the interactions between...
-
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? Model Development: Collaborate with an interdisciplinary team of researchers to integrate data from cohort studies, metabolomics analyses and in vitro experiments, to develop computational models relying on spatial modelling techniques such as cellular Potts and reaction-diffusion models that capture the interactions between...
-
Amsterdam, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? Model Development: Collaborate with an interdisciplinary team of researchers to integrate data from cohort studies, metabolomics analyses and in vitro experiments, to develop computational models relying on spatial modelling techniques such as cellular Potts and reaction-diffusion models that capture the interactions between...
-
Phd Position in Multiscale Spatiotemporal Modelling
4 weken geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdPhd Position in Multiscale Spatiotemporal Modelling of Microbiome During the First 1000 Days of Life **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**:3 juli 2024**Vacaturenummer**:13092- Are you driven by a desire to delve into the convergence of computational...
-
Phd Position in Multiscale Spatiotemporal Modelling
4 weken geleden
Amsterdam, Nederland Universiteit van Amsterdam VoltijdPhd Position in Multiscale Spatiotemporal Modelling of Microbiome During the First 1000 Days of Life **Faculteit/Dienst**:Faculteit der Natuurw., Wiskunde & Informatica**Opleidingsniveau**:Master**Functie type**:Promotieplaats**Sluitingsdatum**:3 juli 2024**Vacaturenummer**:13092- Are you driven by a desire to delve into the convergence of computational...
-
Lab Manager Microbiome Engineering Group
1 week geleden
Amsterdam, Noord-Holland, Nederland Visionatline Voltijd € 3.072 - € 4.103Lab Manager Microbiome Engineering Group. We are currently looking for a Lab Manager / technician to support the work of the newly established group "Microbiome Engineering". The group's mission is to explore the role of the microbiome in human health. Working alongside a team of microbiologists, molecular biologists, biochemists, and neurobiologists, you...
-
Phd Position in Multiscale Spatiotemporal Modelling
1 week geleden
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdPhd Position in Multiscale Spatiotemporal Modelling of Microbiome During the First 1000 Days of LifeFaculteit/Dienst:Faculteit der Natuurw, Wiskunde & InformaticaOpleidingsniveau:MasterFunctie type:PromotieplaatsSluitingsdatum:3 juli 2024Vacaturenummer:13092- Are you driven by a desire to delve into the convergence of computational modelling, omics research,...
-
Phd Position
1 week geleden
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdPhD Position - Artificial Intelligence: Power Asymmetries and Data JusticeFaculteit/Dienst:Faculteit der GeesteswetenschappenOpleidingsniveau:MasterFunctie type:Wetenschappelijk PersoneelSluitingsdatum:8 september 2024Vacaturenummer:13035- Are you looking for a challenging position in a dynamic setting? The Amsterdam School for Cultural Analysis (ASCA)...
-
Postdoc in Microbiome Spatial
1 week geleden
Amsterdam, Noord-Holland, Nederland Universiteit van Amsterdam VoltijdWhat are you going to do ? Within the CarboSupport team, other consortium members have successfully tested and identified combinations of dietary fiber and/or protein that fulfil two key criteria: (i) stimulating the in vitro production of beneficial fermentation products from microbiota sourced from porcine, humans across different age groups, and adult...
