Biophysicist for Therapeutic Molecule Development

2 weken geleden


Amsterdam, Noord-Holland, Nederland AMOLF Voltijd

AMOLF is a leading research institute at the forefront of physics and materials science, driving innovation through fundamental research.

Overview

The Physics of Cellular Interactions group at AMOLF seeks a highly skilled Biophysicist to join their team. The successful candidate will play a crucial role in developing novel therapeutic molecules to modulate T cell receptor signalling.

Our group has made significant advances in single-molecule tracking methods, in vitro assays, and imaging approaches to closely investigate cellular signaling mechanisms. As a member of our team, you will contribute to this exciting research area by analysing the spatiotemporal dynamics of RIPR molecules using single-molecule fluorescence microscopy and single-particle tracking techniques.

Job Description

The primary responsibilities of this position include:

  • Designing and developing novel RIPR molecules to optimally shut down T cell receptor signalling
  • Collaborating with the Fernandes group and other REPRESSIT partners to study the molecular basis of RIPR function
  • Applying biophysical principles to determine general design rules for improving RIPR molecule potency
Requirements

To be considered for this position, candidates must have:

  • A PhD degree in (bio)physics or experimental chemistry
  • Research experience in single-molecule fluorescence techniques or biophysical data analysis
  • Excellent communication and collaboration skills
  • A strong background in coding, preferably Python
Salary and Benefits

The salary for this position starts at €4,065 gross per month, which is in line with the Dutch collective labour agreement for researchers (CAO-OI). Additional benefits include:

  • A full-time appointment (40 hours/week, 12 months/year)
  • A range of employment benefits, including travel compensation and housing support for international applicants
About AMOLF

AMOLF is an international research institute that conducts groundbreaking research in physics and materials science. Our mission is to create new functional materials and push the boundaries of human knowledge. Join us in shaping the future of scientific discovery



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